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Postdoctoral Scientist, Dr. Sean Li
Postdoctoral Scientist, Dr. Sean Li-March 2024
Los Angeles
Mar 28, 2026
About Postdoctoral Scientist, Dr. Sean Li

  Job Description

  Cancer incidence and mortality are generally higher in males than in females, but its underlying biology remains elusive. Bladder cancer is the poster child of cancer sex differences, having male-to-female risk ratios ranking 1st in mortality and 2nd in incidence. Our lab specializes in using cutting edge -omics technologies, a wide range of innovative animal cancer models, and organoids to elucidate the biological mechanisms of sex differences in bladder cancer; we recently published several works that pioneer new concepts on sex as a biological variable in cancers ( DOI: 10.1126/sciadv.aar5598 ; DOI: 10.1126/sciimmunol.abq2630 ).

  We are inviting talented and interested candidates to join our scientific endeavor at the Cedars-Sinai Cancer Institute of Cedars-Sinai Medical Center in Los Angeles—the new home of a well-established research program that first began at Boston Children’s Hospital, Harvard Medical School. Ongoing projects are examining the effects of genetics, epigenetics, immunity and microbiota on the sex and gender disparities in bladder cancer. We also have projects in benign urologic diseases such as bladder regeneration/repair. Successful candidates will have opportunities to hone research, critical thinking, scientific writing, and leadership skills, while taking part in leading a new and budding field of cancer research. This position will also provide incredible opportunities to work on translational disease models with the support of talented clinicians and researchers specializing in cancer biology, epigenome, metabolism, aging, tumor microenvironment, etc.

  Summary:

  The Li Lab is seeking a highly motivated Post-Doctoral Scientist who can work independently while maintaining close collaboration with the Principal Investigator and other Research Scientists. The successful candidate must be able to:

  make significant contributions to project development, experimental design, data collection and interpretation,

  present findings within and outside the lab including departmental and national meetings,

  first author and co-author original research manuscripts. Technical expertise in epigenetics, metabolism, immunity, and/or aging is preferred.

  Essential job Duties and Responsibilities:

  Designs and performs experiments

  Analyzes, interprets, compiles, and summarizes data

  Drafts and publishes findings as first- and co-author

  Researches, develops and implements new laboratory procedures and protocols

  Assists in preparation of grant proposals and presentations

  Performs routine and complex laboratory procedures throughout the training period

  Takes on specific supervisory activities, provide administrative leadership, and/or technical expertise when needed

  Requirement:

  A Ph.D. and/or M.D. degree within the previous 4 years

  A strong track record of productivity

  Strong analytical and problem-solving skills

  Excellent oral and written communication skills in English

  Please apply AND send a (1) cover letter/personal statement (1) CV, and (1) contact information of three references to Dr. Sean Li ( [email protected] ) AND Danielle Hickethier ( [email protected] ).

  Qualifications

  Cancer incidence and mortality are generally higher in males than in females, but its underlying biology remains elusive. Bladder cancer is the poster child of cancer sex differences, having male-to-female risk ratios ranking 1st in mortality and 2nd in incidence. Our lab specializes in using cutting edge -omics technologies, a wide range of innovative animal cancer models, and organoids to elucidate the biological mechanisms of sex differences in bladder cancer; we recently published several works that pioneer new concepts on sex as a biological variable in cancers ( DOI: 10.1126/sciadv.aar5598 ; DOI: 10.1126/sciimmunol.abq2630 ).

  We are inviting talented and interested candidates to join our scientific endeavor at the Cedars-Sinai Cancer Institute of Cedars-Sinai Medical Center in Los Angeles—the new home of a well-established research program that first began at Boston Children’s Hospital, Harvard Medical School. Ongoing projects are examining the effects of genetics, epigenetics, immunity and microbiota on the sex and gender disparities in bladder cancer. We also have projects in benign urologic diseases such as bladder regeneration/repair. Successful candidates will have opportunities to hone research, critical thinking, scientific writing, and leadership skills, while taking part in leading a new and budding field of cancer research. This position will also provide incredible opportunities to work on translational disease models with the support of talented clinicians and researchers specializing in cancer biology, epigenome, metabolism, aging, tumor microenvironment, etc.

  Summary:

  The Li Lab is seeking a highly motivated Post-Doctoral Scientist who can work independently while maintaining close collaboration with the Principal Investigator and other Research Scientists. The successful candidate must be able to:

  make significant contributions to project development, experimental design, data collection and interpretation,

  present findings within and outside the lab including departmental and national meetings,

  first author and co-author original research manuscripts. Technical expertise in epigenetics, metabolism, immunity, and/or aging is preferred.

  Essential job Duties and Responsibilities:

  Designs and performs experiments

  Analyzes, interprets, compiles, and summarizes data

  Drafts and publishes findings as first- and co-author

  Researches, develops and implements new laboratory procedures and protocols

  Assists in preparation of grant proposals and presentations

  Performs routine and complex laboratory procedures throughout the training period

  Takes on specific supervisory activities, provide administrative leadership, and/or technical expertise when needed

  Requirement:

  A Ph.D. and/or M.D. degree within the previous 4 years

  A strong track record of productivity

  Strong analytical and problem-solving skills

  Excellent oral and written communication skills in English

  Please apply AND send a (1) cover letter/personal statement (1) CV, and (1) contact information of three references to Dr. Sean Li ( [email protected] ) AND Danielle Hickethier ( [email protected] ).

  Req ID : 107

  Working Title : Postdoctoral Scientist, Dr. Sean Li

  Department : Research - Hematology and Cellular Therapy

  Business Entity : Cedars-Sinai Medical Center

  Job Category : Academic / Research

  Job Specialty : Postdoctoral Scholar

  Overtime Status : EXEMPT

  Primary Shift : Day

  Shift Duration : 8 hour

  Base Pay : $32.00 - $45.00

  Cedars-Sinai is an EEO employer. Cedars-Sinai does not unlawfully discriminate on the basis of the race, religion, color, national origin, citizenship, ancestry, physical or mental disability, legally protected medical condition (cancer-related or genetic characteristics or any genetic information), marital status, sex, gender, sexual orientation, gender identity, gender expression, pregnancy, age (40 or older), military and/or veteran status or any other basis protected by federal or state law.

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