SENIOR RESEARCH SCIENTIST, DMPK in Buffalo, NY

　　Curia provides global contract research and manufacturing services to the pharmaceutical and biotechnology industries.

　　The Senior Research Scientist, DMPK is an expert in the areas of DMPK and drug bioanalysis and metabolism. The principal responsibilities of the Senior Research Scientist are to execute research projects in these areas, as well as provide technical expertise to prepare cost estimates for non-standard business proposals and to expand capabilities and improve efficiencies for DMPK studies. The Senior Research Scientist is expected to demonstrate expertise in both the theoretical and practical aspects of mass spectrometry, to apply this expertise to the tasks assigned, and to develop novel assays and services as needed. Effective communication and multitasking skills, and the ability to deliver independent results within a team environment are all integral to this position. The Senior Research Scientist is encouraged to display a degree of professionalism reflected in part by increasing the scientist’s knowledge of theory and practice through reading scientific journals and texts. Over time the Senior Research Scientist is expected to demonstrate an aptitude for the mentorship and development of less experienced DMPK scientists.

　　Join our talented workforce, where a commitment to excellence and a customer focused attitude is everything. We pursue excellence because our work has the power to improve patients’ lives with the pharmaceuticals we develop and manufacture.

　　We proudly offer

　　Generous benefit options (eligible first day of employment)

　　Paid training, vacation and holidays (vacation accrual begins on first day of employment)

　　Career advancement opportunities

　　Education reimbursement

　　401k program

　　Pension (for union employees)

　　Learning platform

　　And more!

　　Essential Duties and Responsibilities

　　Provide specific technical expertise to execute research projects in the areas of DMPK, bioanalysis and/or metabolite synthesis

　　Particular focus on bench execution of DMPK assays with ability to cross train (and provide cross training) on additional assays as needed

　　Design and conduct in vitro experiments in liver microsomes or hepatocytes to generate compound metabolites, characterize metabolic pathways, evaluate metabolism kinetics, determine bioactivation mechanisms, etc.

　　Use sound judgment and previously acquired knowledge and experience to develop new procedures. These procedures may go beyond the normal routine and involve literature searching as well as contact with suppliers and customers, etc.

　　Advise and/or train other DMPK scientists for the efficient conduct of ADME assays and appropriate evaluation of assay performance and results

　　Supervision, development and performance monitoring of direct reports and others, as may be assigned by the Head of the DMPK team

　　Education and/or Experience

　　Ph.D. in Biochemistry, Biology, Pharmaceutical Science, Analytical Science, Chemistry or related field with a preference for 1-3 years of relevant industry research experienceOR

　　Master’s degree with at least 8 years of experience in a DMPK laboratory

　　Comprehensive understanding and experience in mass spectrometry, bioanalytical methods development (and validation), in vitro ADME and PK/PD techniques

　　Knowledge, Skills and Abilities

　　Candidate should have fundamental understanding of various DMPK areas such as physicochemical properties, PK, drug metabolizing enzyme and transporter kinetics, and mechanisms of bioactivation

　　Hands-on experience and strong trouble shooting skills for LC-MS/MS bioanalysis

　　Ability to write routine reports and correspondence

　　Salary: $80,500/yr.

　　Education, experience, location and tenure may be considered along with internal equity when job offers are extended.

　　All interested applicants must apply online. Please be aware of scammers. Curia will only send offer letters and requests for sensitive personal information from a curiaglobal.com email address. Curia is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability. Curia is an E-Verify employer.

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