Scientist, CAR-T Flow Cytometry - 2306153815W

　　Description

　　Janssen Research & Development, LLC, a member of Johnson & Johnson's Family of Companies, is recruiting for a Scientist, CAR-T Flow Cytometry located in Malvern, PA.

　　At the Janssen Pharmaceutical Companies of Johnson & Johnson, what matters most is helping people live full and healthy lives. We focus on treating, curing and preventing some of the most devastating and complex diseases of our time. And we pursue the most promising science, wherever it might be found.

　　Janssen Research & Development, LLC discovers and develops innovative medical solutions to address important unmet medical needs in oncology, immunology, neuroscience, infectious diseases and vaccines, cardiovascular and metabolism, and pulmonary hypertension. Please visit http://www.janssenrnd.com for more information.

　　The BioTherapeutics Development and Supply - Analytical Development (BTDS - AD) group is seeking a highly energetic and collaborative Scientist, CAR-T Flow Cytometry, to join our CAR-T Analytical Development team.

　　Principal Responsibilities:

　　Serve as an analytical technical expert for multi-color flow cytometry to support CAR-T product development.

　　Lead method development and optimization to ensure robust assay performance.

　　Provide technical support for troubleshooting and share knowledge/experience with team members.

　　Engage and/or lead technical investigation strategies in support of product investigations with respect to clinical outcomes or adverse events driving to root cause.

　　Effectively communicate scientific data and results across technical teams, project teams, and to the health authority as needed.

　　Collaborate with Quality Assurance and regulatory agencies during audits.

　　Work in a team environment as well as contributing individually to meet project timelines and objectives.

　　Qualifications

　　A minimum of a Master's degree in Biology, Immunology, or a related scientific discipline is required. PhD degree in Biology, Immunology or a related scientific discipline is preferred.

　　A minimum of 6 years of relevant experience with a Master’s degree or a minimum of 2 years of relevant experience with a PhD degree is required.

　　Extensive experience in multi-color flow cytometry including panel design, panel testing/optimization and troubleshooting is required.

　　Knowledge of basic immunology techniques, including mammalian cell culture, immunofluorescence, ELISA, and cell-based potency assays, is required.

　　Hands-on experience with CAR-T or other cell and gene therapy products is preferred.

　　Experience with automation of methods for enhanced throughput is preferred.

　　Chemistry, Manufacturing, and Controls (CMC) experience is preferred.

　　Experience working in a current Good Manufacturing Practice (cGMP) environment is preferred.

　　Knowledge of potency assays and/or cellular immunology is preferred.

　　Must have excellent communication and interpersonal skills.

　　Must be highly organized and capable of managing/pursuing multiple projects independently.

　　The ability to communicate project results, findings and data to management in a clear and timely fashion is required.

　　The ability to work in a cross-functional customer-focused environment is required.

　　This position may require up to 10% domestic travel.

　　Johnson & Johnson is an Affirmative Action and Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, or protected veteran status and will not be discriminated against on the basis of disability.

　　Primary Location NA-US-Pennsylvania-Malvern

　　Organization Janssen Research & Development, LLC (6084)

　　Relocation Eligible: No

　　Job Function Clinical Development & Research - Non-MD

　　Req ID: 2306153815W