Reference #: 1007878SHIFT:Day (United States of America)

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　　A Brief OverviewA research technician position is available in the laboratory of Dr. Brad Lindell within the Department of Anesthesia and Critical Care at Children's Hospital of Philadelphia. Dr. Lindell is a pediatric intensivist who studies mechanisms of immune dysfunction in critically ill pediatric patients in collaboration with clinical and translational scientists throughout CHOP and UPenn.

　　In this position, candidates will employ a range of cellular immunology techniques, including spectral flow cytometry, mass cytometry, transcriptomics, metabolomics, and mitochondrial function assays using human biospecimens. We then apply a systems immunology approach to this multimodal data to develop mechanistic hypotheses of human immune dysfunction in the setting of critical illness.

　　OVERALL RESPONSIBILITIES: After a period of in-lab training by the principal investigator, the applicant will be responsible for independently performing complex immunological assays using fresh and cryopreserved human biospecimens. The candidate will function under the general guidance of the principal investigator, and as part of a team. Depending on candidate background and interest, they may also participate in the writing of project plans, grants, and scientific publications.

　　Candidates must have at least one year of laboratory experience in immunology, cellular and molecular biology, or related fields. Competitive candidates will have experience in flow cytometry, RNA-seq, and translational immunology. Project leadership experience and excellent communication and organizational skills are fundamental to this position. Salary is competitive and will depend upon qualifications and previous training. Institutional assistance obtaining a visa to work in the United States is available. Applicants from backgrounds underrepresented in biomedical research are especially encouraged to apply

　　What you will doPerforms research procedures on experimental samples with minimal supervisionFormulates and performs complex lab experiments and analyzes/ reports the dataPerforms tasks that require knowledge of advanced techniques and lab equipmentPerforms advanced calculations and maintains appropriate log and lab notebooksAssists with planning specific research protocols and proceduresAssists in development & troubleshooting of new techniques and ideasMay be required to modify scientific methods and protocols (in conjunction with PI)Checks others' results for completeness and accuracyMay be responsible for training and mentoring new staffMay assist in the preparation of grants journal articles, posters and oral presentationsMay perform routine and non-routine tests / experiments as neededMaintains office, lab area, reagents, supplies and equipmentPerforms routine maintenance on lab equipmentCoordinates schedules of tests & proceduresAtte ds courses, seminars, and lab meetings to expand knowledge of research and laboratory techniquesRecords results, organizes data and maintains lab notebook in an organized mannerConducts literary searches as requiredEducation QualificationsHigh School Diploma / GED RequiredBachelor's Degree PreferredExperience QualificationsAt least two (2) years of related classroom experience or successful completion of a technical training program (eg. Wistar, WPSI) and research laboratory experience RequiredAt least three (3) years of related classroom experience or successful completion of a technical training program (eg. Wistar, WPSI) and research laboratory experience PreferredSkills and AbilitiesAdvanced understanding of lab procedures, protocols, and equipment.Intermediate proficiency with lab specific experiments / techniques.Intermediate scientific analysis skills.Excellent verbal and written communications skillsExcellent organizational skillsStrong critical thinking / problem-solving skillsStrong analytical skills

　　To carry out its mission, CHOP is committed to supporting the health of our patients, families, workforce, and global community. As a condition of employment, CHOP employees who work in patient care buildings or who have patient facing responsibilities must be fully vaccinated against COVID-19 and receive an annual influenza vaccine.

　　Employees may request exemptions for valid religious and medical reasons. Start dates may be delayed until candidates are immunized or exemption requests are reviewed.

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　　Children's Hospital of Philadelphia is an equal opportunity employer. We do not discriminate on the basis of race, color, gender, gender identity, sexual orientation, age, religion, national or ethnic origin, disability or protected veteran status.