Executive Director - Translational Pharmacology | M/W/D

　　Req ID: 220977

　　Location:

　　Saffron Walden, GB, CB10 1XLManchester, GB, M13 9PLSzeged, HULeiden, NL, 2333 CRKuopio, FI, 70210L'Arbresle, FR, 69592Cambridge, MA, US, 02139Harlow, GB, CM19 5TRSaint Germain Nuelles, FRDen Bosch (S-Hertogenbosch), NL, 5231 DDEvreux, FR, 27930Amsterdam, NL, 1077 ZXFreiburg, DE, 79108Munich, DE, 80538Tranent, GB, EH33 2NE

　　For 75 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe. Whether your background is in life sciences, finance, IT, sales or another area, your skills will play an important role in the work we perform. In return, we’ll help you build a career that you can feel passionate about.

　　Job Summary

　　We are seeking an Executive Director, Translational Pharmacology for our Discovery business.

　　The Executive Director of Translational Pharmacology will be responsible for a global, multidisciplinary team based across several sites in the US and Europe. This senior role requires direct and indirect line management and overall responsibility for the successful delivery of all projects within the group. The disciplines covered by Translational Pharmacology includes in vivo pharmacology across therapeutic areas, and stand-alone DMPK and transporters. The role is a strategic position and requires both internal and external presence across the globe. The Executive Director Translational Pharmacology will be expected to work seamlessly with their colleagues across the Discovery and Safety (DSA) organizations and with international clients to bring in new business.

　　The role reports to the Global Head of Discovery and as such is pivotal in the overall leadership of the Discovery organization. Working closely with other members of the senior team will be required to ensure successful delivery of the overall Discovery objectives.

　　The following are responsibilities related to the Executive Director, Translational Pharmacology :

　　Provide vision, direction, and strong leadership of Translational Pharmacology to foster cooperation and internal synergies across sites. Develop and nurture scientific and discipline excellence to further develop Translational Pharmacology and to scientifically advance Discovery as a whole.

　　Develop short-term and long-term strategic plans to maximize the growth and profitability of Translational Pharmacology and partner with senior leadership to develop long-term strategic business plans for Discovery. Conduct due diligence activities as required and recommend on potential partnerships and M&A.

　　Oversee the establishment and tracking of key performance objectives for management, R&D, scientific, and operations functions and personnel within Translational Pharmacology. Achieve efficient/optimum resource utilization and work collaboratively with other groups to ensure the department and projects are properly resourced, supported and deliver to pre-defined scientific objectives, budget, and timelines.

　　Contribute to the development of major business proposals for key clients and represent the site(s) and company as required. Represent the Company on assigned Joint Steering Committees with key clients. Ensure client expectations are met and any issues involving execution or reporting are resolved in a way that maximizes client satisfaction. Working with direct and indirect reports, maintain a high level of integrity for all aspects of the customer experience within Translational Pharmacology.

　　Develop, implement and manage a program that will continually review processes to ensure that they are efficient and maximize the use of all applicable resources. Where appropriate, harmonize and integrate activities across the various sites, ensuring that synergies are gained, and communications are managed to ensure a seamless interface and delivery to the client.

　　Partner with Human Resources regarding issues and business decisions affecting personnel, including the development of policies and job descriptions, employment actions (hiring, promotions, compensation, disciplinary actions, etc. Oversee the development of a departmental plan for backup and succession of key departmental personnel.

　　Work collaboratively with the finance business partner and peers to ensure Translational Pharmacology is contributing as required to overall Discovery goals. Review and approve budgets. Authorize expenditures in accordance with budget (including capital investments and ROI analysis). Approve budget and expenses of subordinates.

　　Profile and Requirements

　　The following are qualifications related to the Executive Director, Translational Pharmacology position:

　　Education: Minimum Degree level (BSc) within relevant discipline, higher degree (MSc/PhD) preferred.

　　Experience: Substantial related management experience in research or pharmaceutical environment. Extensive drug discovery/development experience in industry, preferably across a range of therapeutic areas. Must have broad experience of management, mentoring, and providing scientific direction to scientists within project teams. Drug discovery experience through to clinical candidate nomination and early development is highly desired.

　　An equivalent combination of education and experience may be accepted as a satisfactory substitute for the specific education and experience listed above.

　　Certification/Licensure: No specific certifications or licensure required

　　Other: Understanding of governmental regulations and guidelines applicable to the care and use of laboratory animals. Knowledge of quality standards and other FDA regulations applicable to non-clinical testing programs. Excellent organizational skills and the ability to meet deadlines. Excellent communication (both written and verbal), leadership and negotiation skills. Ability to interact appropriately with all levels of employees, while at the same time support the efforts of departmental teams. Entrepreneurial attitude with a strong financial acumen.

　　About Discovery

　　Discovery from Charles River is industry-proven in the successful development of novel therapies, with over 350 patents and 80 preclinical drug candidates delivered to our sponsors in the past 17 years. Backed by more than 650 scientists, our comprehensive, integrated portfolio employs the latest technology and platforms to provide chemistry, biology, and pharmacology services that support clients from the earliest stages of hit identification all the way through to IND. Our client-focused, collaborative approach creates true partnerships that anticipate challenges, overcome obstacles, and move us forward together on the journey of getting new drugs to market.

　　About Charles River

　　Charles River is an early-stage contract research organization (CRO). We have built upon our foundation of laboratory animal medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice (GLP) and non-GLP, to support clients from target identification through preclinical development. Charles River also provides a suite of products and services to support our clients’ clinical laboratory testing needs and manufacturing activities. Utilizing this broad portfolio of products and services enables our clients to create a more flexible drug development model, which reduces their costs, enhances their productivity and effectiveness to increase speed to market.

　　With over 20,000 employees within 110 facilities in over 20 countries around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our client’s unique challenges. Our client base includes global pharmaceutical companies, biotechnology companies, government agencies and hospitals and academic institutions around the world.

　　At Charles River, we are passionate about our role in improving the quality of people’s lives. Our mission, our excellent science and our strong sense of purpose guide us in all that we do, and we approach each day with the knowledge that our work helps to improve the health and well-being of many across the globe. We have proudly supported the development of 86% of the drugs approved by the FDA in 2021.

　　At Charles River Laboratories, we recognize and recruit all talent. We are a company committed to the principle of diversity and inclusion and work daily in this direction.