Computational ImmunoDermatology Intern - 2306158146W

　　Description

　　At Johnson & Johnson, we use technology and the power of teamwork to discover new ways to prevent and overcome the world’s most significant healthcare challenges. Our Corporate, Consumer Health, Medical Devices, and Pharmaceutical teams leverage data, real-world insights, and creative minds to make life-changing healthcare products and medicines. We're disrupting outdated healthcare ecosystems and infusing them with transformative ideas to help people thrive throughout every stage of their lives. With a reach of more than a billion people every day, there’s no limit to the impact you can make here. Are you ready to reimagine healthcare?

　　Here, your career breakthroughs will change the future of health, in all the best ways. And you’ll change, too. You’ll be inspired, and you’ll inspire people across the world to change how they care for themselves and those they love. Join us!

　　As a summer Intern in the ImmunoDermatology (Immunology, Translational Sciences) role, you will be a member of a team dedicated to the research and development of precision medicine strategies in inflammatory skin disease.

　　Ability to quickly and quantitatively assess asset PD effect, and patient response to intervention enable go/no go decisions in clinical trials, patient stratification for developing assets, and PD monitoring in in vitro assays. Transcriptomics can capture and unravel disease complexity, but analysis is time consuming, creating a bottle neck in decision process. The proposed project will focus on (a) assembling and curating disease-relevant molecular signatures, based on the literature review and data mining (b) testing signatures across skin and blood cell populations from ongoing studies (c) tracking signatures in datasets from clinical trials, in-house and available from public domain.

　　The goal of this internship program is to provide undergraduate and graduate students experience in working in a large pharmaceutical R&D setting and to gain a basic understanding of the science and process of novel drug development and data-driven approach to personalised medicine. The Intern will be mentored by a highly qualified computational biology leader, with experience both in the industry and academia, and will be embedded in a team of systems biology researchers, including bioinformaticians, computer scientists, and omics platform developers. The Intern will have the opportunity to learn new aspects of disease biology and ways to identify molecular endotypes / drug targets and/or determine the mechanism of action behind emerging drugs. Interns will also receive detailed training on the technology platforms (e.g., single-cell transcriptomics, proteomics, spatial transcriptomics) and analytical methods required for their project, on experimental planning and execution, as well as receive guidance on how to troubleshoot and document data analysis relative to their summer project. This role involves extensive global team matrix interactions with colleagues from a number of different disciplines.

　　The project will be developed jointly by the Intern and their mentor, and the Intern will be expected to present the results of their work to key stakeholders: the project team, the disease area stronghold and as a poster/abstract at the research symposium at the end of the internship.

　　Responsibilities may include:

　　Planning and execution of advanced multi-modal “omics” data analysis

　　Hypothesis-driven data mining

　　Review of literature on disease-specific biology and related new technologies.

　　Data collection and recording keeping.

　　Participating in department and team meetings.

　　Participating in cross-functional team meetings.

　　Shadowing key functional roles for learning/development opportunities.

　　Assisting with interpretation, reporting, and preparation of oral and written results of the analyses performed, in discussion with mentor and other colleagues.

　　Leadership opportunities on specific programs and or group projects.

　　Qualifications

　　Qualifications:

　　Must be currently enrolled in an accredited University or College program throughout the duration of the internship.

　　Undergraduate college students with completion of a minimum of four semesters

　　Must have experience or pursuing a degree in biology, computational biology, cell/molecular biology, biochemistry, genetics, immunology, precision medicine and diagnostics or similar fields

　　Graduate students must be pursuing masters or a PhD degree

　　Must have a minimum cumulative GPA of 3.0 which is reflective of all college coursework

　　Self-motivated, future scientist leaders passionate about drug development and clinical research

　　Detailed oriented with good organizational skills

　　Great interpersonal, verbal and written communication and presentation skills

　　Working knowledge and/or experience using Microsoft suite of business tools including but not limited to Outlook, Excel, and PowerPoint, Word, Teams, Slack, Sharepoint, OneNote, Etc.

　　Ability to analyze data using standard coding-based analytical platforms (e.g., R, Python, etc.)

　　The anticipated base pay for this position is between $21.00 and $40.00, but will be based on candidate’s program year, discipline, degree and/or experience.

　　Johnson & Johnson is an Affirmative Action and Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, or protected veteran status and will not be discriminated against on the basis of disability.

　　Primary Location NA-US-Pennsylvania-Spring House

　　Organization Janssen Research & Development, LLC (6084)

　　Job Function Non-LDP Intern/Co-Op

　　Req ID: 2306158146W