Cambrex

　　Sr. Principal Scientist

　　US-CO-Longmont

　　Job ID: 2023-3548Type: Regular Full-Time

　　of Openings: 1Category: Process ChemistryCambrex - Longmont

　　Overview

　　Cambrex is seeking a highly motivated Sr. Principal Scientist for the ProcessChemistry department. This position performs routine and complex organicsynthesis, purification, and analytical evaluation of materials as part ofa process chemistry research and development team. The chemist will optimizesynthetic routes to active pharmaceutical ingredients for purity,reproducibility, scalability, and yield. Experience in process chemistryresearch and development is desirable. Designs and proposes new syntheticroutes to drug substances. May be asked to lead process chemistry portion ofcustomer projects and potentially a group of process chemists. Presents workinternally and externally to clients or regulatory agencies.

　　Responsibilities

　　Carry out multistep organic syntheses, isolation, and purification oftargeted products independently. Contribute to the strategic approach used tooptimize reactions, isolations, and purifications.Proficiently conduct analysis of starting materials, reaction mixtures,intermediates and products using appropriate instrumentation.Work closely with other chemistry and analytical laboratory staff tocoordinate project activities and resource usage.Routinely generate summaries and reports on completed experimental work forinternal and external use. Routine presentation of experimental work forinternal meetings and teleconferences with customers.Work to ensure that teamwork and cooperation exists within the group at alltimes.Conduct laboratory operations in a safe manner. Maintain familiarity withthe company s chemical hygiene plan. Exhibit safety awareness and safe workpractices.Follow responsible actions regarding chemical disposal. Maintain compliancewith all regulations at the federal, state, and local levels.Address routine administrative requirements in a timely fashion.Demonstrate effective communication skills (both written and oral).Participate in project team meetings with customers.Work closely with manufacturing and GMP operations to coordinateproject-related equipment and activities. Assist in the transfer of processesto the manufacturing team.Independently designs and proposes new synthetic processes to produce thedrug substance.May act as process chemistry lead for customer projects. Identify criticalquestions to be answered and set priorities for the process chemistry team.Maintain familiarity with applicable literature including organic chemistryand techniques.Participate in setting strategy and timing needed for customer proposalrequests.Work closely with other chemistry and analytical laboratory staff tocoordinate project activities and resource usage.Routinely generate summaries and reports on completed experimental work forinternal and external use. Oral and written presentation of experimental workfor internal meetings and teleconferences with customersPerforms other related duties as assigned.Qualifications

　　PhD in Organic Chemistry with 9-12+ years of experience in relatedindustry, or MS in Organic Chemistry with15-18+ years of experience inrelated industry, or BS in Organic Chemistry with 21-24+ years ofexperience in related industry.

　　Advanced to expert understanding of general chemistry and organic chemistry.Understanding of modern organic synthesis reactions, isolations, andpurification procedures.Full understanding of common synthetic organic reaction mechanisms.Understanding and proficient use of all relevant analytical techniques andinstrumentation such as NMR, IR, MS and HPLC.Expertise in laboratory glasEqual Employment Opportunity/M/F/disability/protected veteran status

　　Apply Here: https://www.click2apply.net/pqynZqH562q6MFPGRSA4e

　　PI235604252