About the Role

　　5000+! That's the number of associates in Biomedical Research at Novartis. This division is the innovation engine of Novartis, focusing on powerful new approaches that will help produce therapeutic breakthroughs for patients. The Discovery Sciences department (DSc) at NIBR drives drug discovery and champions innovative approaches such as Radioligand Therapeutics (RLT).

　　The Protein Sciences group is part of Discovery Sciences. We are a highly collaborative group of scientists that produce and study proteins using biophysics and 3D structures to enable target-based approaches including hit identification and validation. We are currently recruiting a Senior Scientist / Principal Scientist with a strong background and track record in protein expression and purification, in particular membrane proteins.

　　The candidate will join our labs in Basel/Switzerland to work on various drug discovery projects in the RLT space and beyond. This is an excellent opportunity to join a vibrant research community at BR in Basel, Switzerland. The successful candidate will be a curious and highly motivated protein scientist with a collaborative team spirit, excellent organizational and communication skills.

　　Location: Basel, Switzerland #LI-Hybrid

　　Your responsibilities:

　　Your responsibilities include, but are not limited to:

　　• Contribute experimentally and intellectually to early drug discovery projects within multidisciplinary teams

　　• Produce proteins for hit generation and hit validation activities as well as biophysics and structural biology studies

　　• Innovate and further develop existing experimental procedures and implement novel technologies

　　• Work closely with lab associates in a matrix setting, including the mentoring and development of junior team members

　　• Present and communicate results at internal and external meetings and in scientific publications

　　Diversity & Inclusion / EEO

　　We are committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve.

　　Role Requirements

　　• PhD degree in biochemistry, life sciences, molecular biology or related field, or equivalent relevant research experience in an academic setting and/or in the pharmaceutical/biotech sector

　　• Demonstrated experience with expression, purification, and modification of a range of protein targets; experience with mammalian and insect cell expression systems is a strict requirement, experience with membrane proteins will be considered a strong asset

　　• Proficiency in construct design and tagging strategy using pioneering tools

　　• Mentoring and training skills to develop team members

　　• Analytical skills and an eye for detail to ensure accurate record keeping of high quality data

　　• Excellent communication and presentation skills in oral and written English.

　　• Strong team spirit and a collaborative approach

　　Desirable Requirements:

　　• Prior experience with purification optimization for protein-based assays (eg screening, biophysics or structural biology), including detergent optimization screening

　　• Experience with characterizing protein ligand interactions

　　• Curiosity to explore novel methods and innovative technologies

　　• Experience with protein tracking databases and or workflow tools

　　Why Novartis: Our purpose is to reimagine medicine to improve and extend people's lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here:

　　https://www.novartis.com/about/strategy/people-and-culture

　　You'll receive: You can find everything you need to know about our benefits and rewards in the Novartis Life Handbook. https://www.novartis.com/careers/benefits-rewards

　　Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to

　　[email protected] and let us know the nature of your request and your contact information. Please include the job requisition number in your message.

　　Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network

　　Division

　　Biomedical Research

　　Business Unit

　　DSc

　　Location

　　Switzerland

　　Site

　　Basel

　　Company / Legal Entity

　　Novartis Pharma AG

　　Functional Area

　　Research & Development

　　Job Type

　　Full Time

　　Employment Type

　　Regular

　　Shift Work

　　No