HOW MIGHT YOU DEFY IMAGINATION?

　　You’ve worked hard to become the professional you are today and are now ready to take the next step in your career. How will you put your skills, experience and passion to work toward your goals? At Amgen, our shared mission—to serve patients—drives all that we do. It is key to our becoming one of the world’s leading biotechnology companies, reaching over 10 million patients worldwide. Come do your best work alongside other innovative, driven professionals in this meaningful role.

　　Senior Scientist – Inflammation Target Evaluation and Targeted Protein Degradation

　　Live

　　What you will do

　　Let’s do this. Let’s change the world. In this vital role you will be a part of Amgen’s Induced Proximity Platform (IPP) organization. The IPP team is focused on developing novel drug modalities that use proximity biology to go after challenging drug targets in diverse therapeutic areas, such as Oncology, Cardiometabolic disorders and Inflammation. The Target Evaluation group in IPP is seeking a motivated Senior Scientist to work closely with the Inflammation group and support early discovery work evaluating therapeutic targets for IPP modalities such as heterobifunctional molecules and molecular glues. The successful candidate will also work collaboratively with teams within IPP to broaden our understanding of emerging IPP technologies and their application.

　　Responsibilities:

　　Set project goals and timelines, design, perform, and analyze experiments to evaluate novel inflammation targets and establish a differentiating strategy for an IPP modality.

　　Experimentally validate emerging IPP tools and technologies and their application.

　　Interact with IPP team members and members across different departments and research sites and communicate and present data to department leadership.

　　Contribute results and participate in the writing of manuscripts for publication.

　　Win

　　What we expect of you

　　We are all different, yet we all use our unique contributions to serve patients. The dynamic professional we seek is a strong collaborator with these qualifications.

　　Basic Qualifications:

　　Doctorate degree (and relevant post-doc where applicable)

　　Or

　　Master’s degree and 3 years of Immunology experience

　　Or

　　Bachelor’s degree and 5 years of Immunology experience

　　And

　　Advanced and proficient understanding and use of technical principles, theories, and concepts to perform an expansive range of work in a role

　　And

　　Basic knowledge of related and adjacent disciplinary areas.

　　Preferred Qualifications:

　　A PhD degree in an immunology-related field.

　　Understanding of the ubiquitin proteasome system is preferred.

　　Expertise in T cell, myeloid, and B cell biology is essential.

　　Strong technical skills or expertise in inflammation related functional assays.

　　Experience with standard cell and molecular biology experimental design and techniques such as cell culture, lentiviral production, stable cell line generation, western blot, and qPCR.

　　Experience with gene knockdown techniques such siRNA, shRNA or CRISPR.

　　Experience with multi-color flow cytometry and high throughput assays such as CTG, HiBiT, or live cell imaging techniques such as Incucyte.

　　A track record of scientific achievement, supported by publications and/or significant contributions to a drug discovery program.

　　Excellent organizational, interpersonal and communication skills.

　　Flexibility to work in teams to achieve changing project goals and meet timelines.

　　Strong data analysis and independent critical thinking skills.

　　Thrive

　　What you can expect of us

　　As we work to develop treatments that take care of others, we also work to care for our teammates’ professional and personal growth and well-being.

　　Amgen offers a Total Rewards Plan comprising health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities including:

　　Comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts.

　　A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan

　　Stock-based long-term incentives

　　Award-winning time-off plans and bi-annual company-wide shutdowns

　　Flexible work models, including remote work arrangements, where possible

　　Apply now

　　for a career that defies imagination

　　Objects in your future are closer than they appear. Join us.

　　careers.amgen.com

　　Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

　　We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.