AbbVie is recruiting for a Sr. Scientist II, Drug Substance Development position in the Department of Neurotoxin & Biologics Process Sciences (NBPS), at its Irvine, CA site.

　　The Sr. Scientist II, Drug Substance Development will be an instrumental team member of the NBPS group. The primary focus of this position is to lead the drug development and optimization studies for natural and recombinant proteins (including neurotoxins) from bacterial cultures during early discovery and process development. In particular, the candidate is expected to perform and support process mapping for drug substance manufacturing process. The desired candidate will have a solid understanding and hands-on work experience with biologics process development, fermentation, protein separation, characterization, and small-scale experimental designs. The successful candidate will perform laboratory work, develop productive collaborations and communications with other groups across scientific disciplines and be motivated to innovate and succeed in a fast-paced, collaborative environment. The role requires evaluating new technologies relevant to upstream, harvest and downstream processes to enhance process understanding.

　　The Sr. Scientist II will work closely with members of the upstream, downstream, and analytical development groups in creating a collaborative environment for advancement of robust manufacturing processes. The successful candidate is expected to lead research and development studies, author research protocols/reports and present findings in the multidisciplinary team environment. The position will represent the department and participate in cross-functional project team meetings. The ideal candidate will exhibit leadership skills that enable good performance and career development of junior staff and possess excellent communication (oral and written) and interpersonal skills.

　　Qualifications

　　BS, MS, or PhD in Pharmaceutical Sciences, Microbiology, Biochemistry, Chemical engineering, or closely related field is required.

　　Bachelor’s Degree with 12 years of experience, master’s degree with 10 years of experience or PhD and 4 years of industry or post-doc experience.

　　Experiences in fermentation and downstream processing, as well as statistical experiment design/data analysis skills are highly desired.

　　Familiarity with pharmaceutical regulations and guidelines (Example: FDA, MAA, EMA).

　　Experience in developing novel manufacturing technologies is highly desirable. Ability to drive continuous improvements.

　　Proven ability to work independently, effectively plan and organize work activities, and prioritize task completion to meet project deadlines in a fast-paced industrial environment required.

　　Excellent oral and written communication skills required as is experience with documentation of experimental plans, analyzing data and generating high quality technical reports.

　　Ability to work on-site

　　*Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:

　　The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future.

　　We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.

　　This job is eligible to participate in our short-term incentive programs.

　　This job is eligible to participate in our long-term incentive programs.

　　Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law.

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　　AbbVie is committed to operating with integrity, driving innovation, transforming lives, serving our community, and embracing diversity and inclusion. It is AbbVie’s policy to employ qualified persons of the greatest ability without discrimination against any employee or applicant for employment because of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information, gender identity or expression, sexual orientation, marital status, status as a protected veteran, or any other legally protected group status.