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Senior Principal Scientist
Senior Principal Scientist-March 2024
Groton
Mar 16, 2026
ABOUT PFIZER
Pfizer is a pharmaceuticals and biotechnology company.
10,000+ employees
Biotechnology, Manufacturing
VIEW COMPANY PROFILE >>
About Senior Principal Scientist

  Why Patients Need You

  Pfizer's purpose is to deliver breakthroughs that change patients' lives. Research and Development is at the heart of fulfilling Pfizer's purpose as we work to translate advanced science and technologies into the therapies and vaccines that matter most. Whether you are in the discovery sciences, ensuring drug safety and efficacy or supporting clinical trials, you will apply cutting edge design and process development capabilities to accelerate and bring the best-in-class medicines to patients around the world.

  What You Will Achieve

  At Pfizer, we are always seeking to deliver breakthroughs that change patients' lives. In this role, you'll be working to help us achieve that goal by advancing biotechnologicallyderived products to the market through innovation and delivery of cutting-edge analytical testing. You will be part of a team which is focused on developing methods and strategies to support product and process development for small molecules, at all stages of clinical development. You willwork across analytical functions and projects.

  A Senior Principal Scientist in Analytical Research and Development plays an important role during all phases of pharmaceutical development. The qualified candidate will take an active role by leading the analytical development strategies and performing and directing lab work for new drug candidates. The candidate will work with cross-functional development teams and apply a variety of analytical methodologies to support physical and chemical characterization of drug substances and products. The candidate should be proficient with a breadth of analytical methodologies (e.g. chromatography, mass spectrometry, dissolution, spectroscopy, and NMR), with expertise in one or more techniques. The candidate should also be proficient with a wide variety of software and information systems and have a demonstrated ability to learn new techniques and solve complex analytical problems. Experience with mathematical modeling or coding is also desired.

  It is your hard work and dedication that will make Pfizer ready to achieve new milestones and help patients across the globe.

  How You Will Achieve It

  As a project analyst, the candidate will be responsible for developing analytical strategies in support of pharmaceutical drug products during all development phases, including supporting manufacturing process development, developing, validating and transferring analytical methods, designing stability studies to understand drug degradation mechanisms and for shelf life assignments, and developing impurity control strategies.

  The candidate will perform lab work and will plan, direct, and review the lab work of other scientists in a matrix environment.

  The role requires collaboration with colleagues to identify appropriate analytical approaches, including use of computational predictive tools, modeling software and data visualization tools where appropriate.

  The candidate will critically review and Interpret scientific data to derive clear conclusions and provide direction for future work and will communicate results and conclusions through various media including presentations and technical reports.

  As a subject matter expert, the candidate will evaluate new approaches, instrumentation or analytical technologies and mentor other scientists.

  The candidate will author relevant sections of the quality modules of regulatory submissions.

  Qualifications

  BASIC QUALIFICATIONS

  Ph.D in Analyical Chemistry or related field, with 7+ years of pharmaceutical R&D experience required

  Demonstrated oral and written communication skills, including visualization of data, presentations and authoring technical articles.

  Demonstrated ability to meet timelines and interact with multi-disciplinary teams

  Demonstrated ability to learn new techniques and solve complex analytical problems.

  Attention to detail, strong organizational skills, and effective interpersonal and communication skills are required.

  Proficient with a wide variety of software and information systems.

  PREFERRED QUALIFICATIONS

  Working knowledge and the ability to operate analytical techniques such as HPLC-MS, GC-MS, spectroscopy, and physical techniques such as particle size and dissolution that are commonly used for the characterization of pharmaceutical substances and products is desired.

  Candidate demonstrates a breadth of diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact.

  Candidate demonstrates a breadth of diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact.

  PHYSICAL/MENTAL REQUIREMENTS

  Role requires ability to perform mathematical calculations and complex data analysis.

  NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS

  Role requires adherence to standard operating procedures. Some travel may also be required. Ability to work in a laboratory setting

  Additional Information:

  Relocation support available

  Eligible for Employee Referral

  Work Location Assignment:On Premise

  Last Day to Apply: February 6, 2024

  The annual base salary for this position ranges from $117,300.00 to $195,500.00. In addition, this position is eligible for participation in Pfizer's Global Performance Plan with a bonus target of 17.5% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life's moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site - U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.

  Relocation assistance may be available based on business needs and/or eligibility.

  Sunshine Act

  Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

  EEO & Employment Eligibility

  Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

  Research and Development

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