Senior Manager/Associate Director, HEOR

　　Do you want to be part of an inclusive team that works to develop innovative therapies for patients? Every day, we are driven to develop and deliver innovative and effective new medicines to patients and physicians. If you want to be part of this exciting work, you belong at Astellas!

　　Astellas Pharma Inc. is a pharmaceutical company conducting business in more than 70 countries around the world. We are committed to turning innovative science into medical solutions that bring value and hope to patients and their families. Keeping our focus on addressing unmet medical needs and conducting our business with ethics and integrity enables us to improve the health of people throughout the world. For more information on Astellas, please visit our website at www.astellas.com .

　　This position is based in Northbrook, Illinois. Remote work may be permitted in accordance with Astellas’ Responsible Flexibility Guidelines. Candidates interested in remote work are encouraged to apply.

　　Purpose and Scope:

　　Responsible for pro-actively formulating, consolidating, and implementing Astellas HEOR strategies and ensuring that (sub)regional HEOR perspectives and strategies are integrated within the MA core medical plans, integrated global value plans, integrated evidence generation plans, brand plans, and launch excellence plans.

　　Responsible for development, management and delivery of regional and adapted local health economic, comparative effectiveness, patient reported outcomes, and epidemiologic data, and real world evidence, budgetary impact and cost effectiveness analyses/-modeling, Health Technology Assessment including early scientific advice and assessments post-approval for assigned in-line and late-stage development compounds that are medically relevant, scientifically and technically valid, address business needs, support patient access and HTA/reimbursement requirements

　　This position requires excellent interpersonal and matrix leadership skills to support effective partnerships with key internal and external stakeholders including global/regional/local HEOR leaders, Department Heads, TA Heads, CMT Leads, Development, Regulatory Affairs, and Market Access.

　　Essential Job Responsibilities:

　　Medical Affairs Leadership

　　Co-create development of integrated global value plan, provide regional input into integrated global brand plan

　　Responsible to develop HEOR strategies and tactics that are evidence based, scientifically and technically valid, and medically relevant; of clinical, humanistic, and economical importance; patient focused; integrated in the Core Medical Plans and integrated evidence generation plans, and address the needs of regional, HTA, payers, patients, health care providers, and policy makers and regulators and in line with regional brand plan

　　Responsible for successful execution of all MA HEOR activities and deliverables for assigned product across (sub)region and to ensure these are delivered with high quality and within timelines and budget

　　Oversee regional and local adaptation of core value dossiers and core economic models to local HTA requirements and ensure alignment with the global value messages

　　Departmental and People Leadership

　　Serve on organizational initiatives and taskforces as appropriate to shape the strategic direction of the sub-regional and global HEOR function Matrix Leadership

　　Actively participate global value team and core health economics team

　　Maintains an integrated partnership within global/regional/local Medical Affairs and cross functional colleagues including Market Access to identify collaborative opportunities, ensure optimal alignment, leverage resources, and support business priorities

　　Actively promote strategic collaborations with other Astellas HEOR colleagues across the globe to share and replicate best practices and advance HEOR initiatives to support the Astellas product portfolio and patient access

　　Scientific / HEOR technical Expertise

　　Maintains in depth knowledge of Astellas products/disease states for assigned products

　　Support preparation and coordination for HTA/payer advice, mock preparations, submissions, face to face meetings and objection handling in region

　　Actively monitor the changing healthcare landscape to identify emerging regional HEOR trends

　　Maintain in depth knowledge about patient access and HTA/reimbursement requirements, processes and best practices to inform HEOR strategies

　　Represent Astellas on HEOR issues at regional / global forums, conferences and professional associations and trade associations; including monitoring ad communicating activities by such forums to executive leadership

　　Medical Governance

　　Provide oversight and strategic and scientific input for HEOR projects, data interpretation, protocol development, regulatory documents, scientific publications, and independent research proposals for assigned products within assigned region

　　Ensure the timely completion of assigned HEOR projects that include appropriate outcome assessments, analysis plans and final reports with expectations for peer-reviewed publications relevant to HEOR evidence generation strategies

　　Ensures all HEOR deliverables support Astellas’ commitment to integrity and delivery of the highest standard of quality and in compliance with all applicable regulations, external policies and ethical standards

　　Quantitative Dimensions:

　　The Regional HEOR Product Lead develops innovative, cutting edge economic, epidemiological and clinical outcomes data generation activities and related medical tools (appr 10 annually) across assigned products that are designed to shape the medical value proposition for Astellas products throughout their life cycle. The HEOR Regional Product Lead will provide matrix leadership to represent local and (sub)regional HEOR within the GVT. The role has a (sub)regional scope and is supporting all countries within (sub)region with no country resources, overseeing all countries in region’s needs.

　　He/she is accountable for managing resources, priorities and workload across products and includes direct budget responsibilities of $1-1.5 mln annually. The results produced by the HEOR Regional Product Lead must be scientifically sound and in compliance with applicable regulations.

　　Organizational Context

　　The HEOR Regional Product Lead reports to the Regional HEOR (TA) Lead. They will have multiple cross-functional collaborative project teams and matrix responsibility across the broader Astellas organization. The HEOR Regional Product Lead will collaborate with the following colleagues:

　　Medical Affairs: TA Heads, Executive Directors, CMT leads, Senior Medical Directors/CMT members, HEOR Leaders

　　Market Access: Senior Directors

　　Other: Senior Director/Director Legal, Ethics & Compliance, Brand General Managers

　　External: Executive leadership of Astellas partners and organizations

　　Qualifications

　　Required

　　Advanced Degree (PharmD, PhD, MD) with consideration for MPH or other advanced degree inLife Sciences, HE or Epidemiology with relevant advanced industry experience

　　3 years relevant experience in at least one of the following fields: Outcomes Research, HE, Clinical Research, Epidemiology, Health Policy

　　Demonstrated strategic thinking, problem solving and decision-making skills

　　Expertise in understanding interface between clinical practice and outcomes research

　　Expertise in leveraging outcomes data in the appropriate clinical context

　　Demonstrated strong interpersonal relationship and collaboration skills working within cross functional teams

　　Thorough understanding of global guidelines as they relate to HEOR and Medical Affairs

　　Expertise in global HTA/payer reimbursement and market access requirements

　　A collaborative style of working and a strong sense of ethics, compliance and integrity

　　Excellent written and verbal communication and presentation skills Expertise in HEOR including principles, pharmaceutical research design and methods as well as excellent project and vendor management skills

　　Benefits

　　Medical, Dental and Vision Insurance

　　Generous Paid Time Off options, including Vacation, Sick time, plus national holidays including Heritage Days, and Summer and Winter Breaks

　　401(k) match and annual company contribution

　　Company paid life insurance

　　Annual Corporate Bonus and Quarterly Sales Incentive for eligible positions

　　Long Term Incentive Plan for eligible positions

　　Referral bonus program

　　Astellas is committed to equality of opportunity in all aspects of employment. EOE including Disability/Protected Veterans.

　　Category Medical Affairs - USA

　　Astellas is committed to equality of opportunity in all aspects of employment.

　　EOE including Disability/Protected Veterans