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Postgraduate in LVV producer cell line engineering
Postgraduate in LVV producer cell line engineering-July 2024
Basel
Jul 2, 2025
ABOUT NOVARTIS
At Novartis, we’re reimagining medicine to improve people’s lives through innovative science and technology.
10,000+ employees
Biotechnology
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About Postgraduate in LVV producer cell line engineering

  About the Role

  The Biologics Research Center (BRC) at Novartis Biomedical Research (BR) discovers, develops, and innovates Biotherapeutics from therapeutic proteins to cell and gene therapies. We are looking for a highly motivated intern who recently received a M.Sc. degree with a strong scientific curiosity and interest in cell culture technologies and cell & gene therapy. The intern will advance the innovation pipeline of our lentiviral vector (LVV) manufacturing platform.

  Preferred start date: May 2024

  Latest start date: June 2024

  Duration: 10 months

  Key responsibilities:

  • Perform state-of-the-art HEK (stable) cell line engineering/generation activities to improve LVV titers and quality through cutting-edge gene editing technologies

  • Execute LVV productions and determine quality by target cell transduction with ddPCR & Flow Cytometry, Western Blot, sgPERT and genome integrity analysis

  • Support cell & molecular biology characterization of engineered cell lines using appropriate methods such as Flow Cytometry, NGS & qPCR

  • Document experiments using electronic lab book and according to line function requirements

  • Analyze and collect experimental data & present scientific interpretation in internal meetings

  #LI-Onsite

  Diversity & Inclusion / EEO

  We are committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve.

  Role Requirements

  Essential requirements:

  • Recent Master graduate (up to 6 months) with a degree in Biotechnology, Biology, Bioengineering, Biochemistry or similar

  • Proficient in English (written and spoken)

  • Experience/Professional requirements:

  o Experience in cell culture, desirable HEK (suspension) cell culture

  o Excellent team player

  Desirable requirements:

  • Good experience of working in Biosafety level 2 environment.

  • Good experience in the production of retroviruses (ideally LVVs) is of advantage

  • Experience with gene editing techniques (CRISPR), RNAi and FACS is of advantage

  Why Novartis: Our purpose is to reimagine medicine to improve and extend people's lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture

  Accessibility and accommodation:

  Novartis is committed to working with and providing reasonable accommodation to all

  individuals. If, because of a medical condition or disability, you need a reasonable

  accommodation for any part of the recruitment process, or in order to receive more detailed

  information about the essential functions of a position, please send an e-mail to

  [email protected] and let us know the nature of your request and your

  contact information. Please include the job requisition number in your message

  Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network

  Division

  Biomedical Research

  Business Unit

  BIOLOGICS NIBR

  Location

  Switzerland

  Site

  Basel

  Company / Legal Entity

  Novartis Pharma AG

  Functional Area

  Interns/Students on Novartis Payroll

  Job Type

  Full Time

  Employment Type

  Internship

  Shift Work

  No

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