About the Role

　　The Biologics Research Center (BRC) at Novartis Biomedical Research (BR) discovers, develops, and innovates Biotherapeutics from therapeutic proteins to cell and gene therapies. We are looking for a highly motivated intern who recently received a M.Sc. degree with a strong scientific curiosity and interest in cell culture technologies and cell & gene therapy. The intern will advance the innovation pipeline of our lentiviral vector (LVV) manufacturing platform.

　　Preferred start date: May 2024

　　Latest start date: June 2024

　　Duration: 10 months

　　Key responsibilities:

　　• Perform state-of-the-art HEK (stable) cell line engineering/generation activities to improve LVV titers and quality through cutting-edge gene editing technologies

　　• Execute LVV productions and determine quality by target cell transduction with ddPCR & Flow Cytometry, Western Blot, sgPERT and genome integrity analysis

　　• Support cell & molecular biology characterization of engineered cell lines using appropriate methods such as Flow Cytometry, NGS & qPCR

　　• Document experiments using electronic lab book and according to line function requirements

　　• Analyze and collect experimental data & present scientific interpretation in internal meetings

　　#LI-Onsite

　　Diversity & Inclusion / EEO

　　We are committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve.

　　Role Requirements

　　Essential requirements:

　　• Recent Master graduate (up to 6 months) with a degree in Biotechnology, Biology, Bioengineering, Biochemistry or similar

　　• Proficient in English (written and spoken)

　　• Experience/Professional requirements:

　　o Experience in cell culture, desirable HEK (suspension) cell culture

　　o Excellent team player

　　Desirable requirements:

　　• Good experience of working in Biosafety level 2 environment.

　　• Good experience in the production of retroviruses (ideally LVVs) is of advantage

　　• Experience with gene editing techniques (CRISPR), RNAi and FACS is of advantage

　　Why Novartis: Our purpose is to reimagine medicine to improve and extend people's lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture

　　Accessibility and accommodation:

　　Novartis is committed to working with and providing reasonable accommodation to all

　　individuals. If, because of a medical condition or disability, you need a reasonable

　　accommodation for any part of the recruitment process, or in order to receive more detailed

　　information about the essential functions of a position, please send an e-mail to

　　[email protected] and let us know the nature of your request and your

　　contact information. Please include the job requisition number in your message

　　Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network

　　Division

　　Biomedical Research

　　Business Unit

　　BIOLOGICS NIBR

　　Location

　　Switzerland

　　Site

　　Basel

　　Company / Legal Entity

　　Novartis Pharma AG

　　Functional Area

　　Interns/Students on Novartis Payroll

　　Job Type

　　Full Time

　　Employment Type

　　Internship

　　Shift Work

　　No