The Wang Laboratory at MD Anderson Cancer Center is a computational biology research lab. We apply innovative bioinformatics approaches to dissect the tumor 'ecosystem', deeply profile tumor cells and cells of the tumor microenvironment as well as tumor-immune-stroma crosstalk at single-cell resolution and in the spatial context. The lab's key focus areas include: 1) Transition from premalignant lesions to invasive cancer; 2) Evolution of metastasis from a localized tumor; 3) Dynamic response to anti-cancer therapies and the development of therapeutic resistance. Leveraging cutting-edge single-cell and spatial multi-omics technologies, cellular imaging, and innovative bioinformatics tools and computational frameworks, we aim to harness the potential of big data to fight cancer. Our overarching goal is to advance our understanding of the cellular & molecular cues underlying early tumorigenesis, disease progression, and the development of therapy resistance and translate our novel discoveries into improved patient care. We are seeking multiple talented and highly motivated Postdoctoral Fellows with a strong background in bioinformatics and a passion for exploring the heterogeneity and evolution of tumor cells and tumor microenvironment using the state-of-the-art single cell and spatial multi-omics approaches.

　　LEARNING OBJECTIVES

　　Gain skills in single cell, spatial omics, and imaging data analysis, immunogenomics, immune-informatics, and cancer-specific bioinformatics. Develop expertise in study design, data analysis, data interpretation, presentation, manuscript and grant writing

　　ELIGIBILITY REQUIREMENTS

　　Individuals with a PhD degree in computational biology, bioinformatics, data science or a related field are encouraged to apply. A strong computational background, proficiency in R and at least one additional scripting language (e.g., Python) and knowledge in biostatistics are required. Experience working with single cell and spatial omics data analysis and high-performance computing environment (Unix/Linux) is highly preferred. A good understanding of cancer biology, immunology, cell biology, and molecular biology is also preferred. Proven track record of publications, excellent spoken and written communication skills are required

　　ADDITIONAL APPLICATION INFORMATION

　　Interested applicants should send a Cover Letter specifying past research experience/skills/accomplishments, a Curriculum Vitae and the contact information of three (3) Referees to Dr. Linghua Wang at [email protected] with the subject line entitled "Postdoctoral Fellow - Application - Applicant's Name".

　　POSITION INFORMATION

　　MD Anderson follows the NIH stipend levels as outlined by the Kirchstein - NRSA (https://grants.nih.gov/grants/guide/notice-files/NOT-OD-23-076.html) . This full-time trainee position will provide a salary between $56,484 to $68,604, dependent upon the years of postgraduate experience.

　　MD Anderson offers compensated trainees:

　　Paid medical benefits (zero premium) starting on first day for trainees who work 30 or more hours per week

　　Group Dental, Vision, Life, AD&D and Disability coverage

　　Paid Education Vacation and Sick Leave

　　Paid institutional holidays, wellness leave, childcare leave and other paid leave programs

　　Teachers Retirement System defined-benefit pension plan and two voluntary retirement plans

　　Employer paid life, AD&D and an illness-related reduced salary pay program

　　Health Savings Account and Dependent Care Reimbursement flexible spending accounts

　　Fertility benefits

　　State of Texas longevity pay

　　Extensive wellness, fitness, employee health programs and employee resource groups

　　FACULTY MENTOR

　　Dr. Linghua Wang