Highly motivated individuals with a PhD or MD/PhD in relevant area are encouraged to apply. This training position, under the direct supervision of a Cleveland Clinic Principal Investigator will provide practical training and experience in a research setting. This position is appointed through the Lerner Research Institute. The successful applicant will be able to demonstrate a commitment to research, a collaborative work ethic and strong communication skills, both written and verbal. This program is expected to be completed within 5 years.

　　The Stolley Lab, located in the department of Inflammation and Immunity at the Cleveland Clinic Lerner Research Institute, seeks a motivated postdoctoral scientist to conduct research at the confluence of immunology and oral biology. The mouth encompasses a truly unique constellation of barrier, absorptive, secretory, and chemosensory tissues, and is continuously bombarded by myriad environmental, chemical, mechanical, and pathogenic insults. However, in contrast to other mucosal locations (e.g., the gut), the immunobiology of the oral mucosa remains comparatively underexplored.

　　The Stolley Lab is broadly interested in understanding how immune cells integrate within the distinctive environment of the mouth to mediate local immunosurveillance and tissue homeostasis. Specifically, we seek to characterize how T cell responses in the oral mucosa impact periodontal health, saliva production/composition, chemoreception (taste and smell), and the oral microbiota. Furthermore, we are interested in co-opting the inflammatory functions of mouth-resident T cells against oral cancer.

　　Established August 2023, the Stolley Lab leverages mouse models of periodontitis, oral infection, and oral cancer to fill these knowledge gaps with the goal of translating our findings into novel therapeutic strategies to improve human oral health.

　　Principal Investigator: J. Michael Stolley, PhD

　　Lerner Research Institute Department: Inflammation & Immunity

　　Lab Research Topics:

　　Immunology

　　T cell biology

　　Oral Mucosal Immunology

　　Chemosensory biology

　　Oral Cancer

　　For more information about the lab's research, please contact Dr. Michael Stolley at [email protected]

　　Job Responsibilities:

　　Independent project design with the goal of data generation, analysis, interpretation and manuscript preparation

　　Plan and perform independent experiments

　　Analyze and interpret data

　　Report findings and prepare and manuscripts

　　Help maintain laboratory operations

　　Education:

　　PhD or MD/PhD requiredLanguages:

　　English Proficiency proof required for candidates arriving on J-1, J-2, or F1 + OPT visa statusWork Experience:

　　Previous experience in a research or academic setting. Graduate student experience meets this requirement.

　　Scientific writing experience

　　Additional Preferred Qualities:

　　Previous experience working with mice

　　Flow cytometry and microscopy experience

　　Good communication skills

　　Previous publications in high-impact journals

　　Previous experience with mouse necropsy

　　Physical Requirements:

　　Ability to perform work in a stationary position for extended periods

　　Ability to operate a computer and other office equipment

　　Ability to communicate and exchange accurate information

　　Ability to distinguish color

　　Manual dexterity to handle specimens and repair equipment

　　Ability to lift and transport equipment or specimens weighing up to 20 pounds

　　May be exposed to hazardous chemicals, bio-hazards, radioactive materials, etc.

　　Personal Protective Equipment:

　　PPE per institutional requirements; may vary by laboratoryPreferred Application Materials:

　　CV

　　1-2 page research statement

　　Contact information for three referees

　　All application materials should be submitted directly via email to Michael Stolley at [email protected] .

　　Keywords: Postdoc, Research, LRI, Saliva, Complement, Autoimmunity, Sjogren's, Behavior, Animal, Resident memory, Adaptive immunity, Gum disease, OSCC, Immunotherapy

　　Pay Range

　　Minimum hourly: $0.01

　　Maximum hourly: $333,340.26

　　The pay range displayed on this job posting reflects the anticipated range for new hires. While the pay range is displayed as an hourly rate, Cleveland Clinic recruiters will clarify whether the compensation is hourly or salary. A successful candidate's actual compensation will be determined after taking factors into consideration such as the candidate's work history, experience, skill set, and education. This is not inclusive of the value of Cleveland Clinic's benefits package, which includes among other benefits, healthcare/dental/vision and retirement.

　　Cleveland Clinic Health System is pleased to be an equal employment employer: Women / Minorities / Veterans / Individuals with Disabilities