At Editas, we’re driven by a collective purpose, to bring transformative and life changing therapies to people living with serious diseases with the greatest unmet needs. This fuels our drive to excel in scientific innovation, allowing us to harness the power and potential of CRISPR/Cas9 and CRISPR/Cpf1 (Cas12a) gene editing.

　　We believe our people are at the core of everything we do, and we’re committed to cultivating a culture where every individual feels valued and included. To do this, we strive to integrate belonging, inclusivity, diversity, and equity into every aspect of our organization.

　　Together, we are leading the way towards a healthier and more equitable future.

　　Position Summary

　　Editas is seeking a highly motivated Manager for our Platform Technology Group. In this role, you will develop cellular assays, and lead your team to deploy lab automation solutions for research, clinical development, and manufacturing applications. You will work with other scientists and project teams to develop/adapt, scaleup, test and standardize key assays and processes in both research and clinical development, having a direct impact on the newest genomic medical advancements.

　　In addition, the manager will generate and QC research grade editing reagents and document information in our LIMS system. Reagent orders are requested through our LIMS and JIRA systems, and stakeholders will need to be updated on a weekly basis on the status of the requests.

　　An ideal candidate should have a strong background in scaling up cellular, biochemical and assays using a wide range of laboratory automation. This includes liquid handling robots, such as the Biomek I7, acoustic liquid transfer, such as the Echo and automated sample storage systems, such as the Hamilton SAM. The candidate will help put together yearly budgets for screening projects and automation.

　　The position will report to the Sr. Director of Platform Technologies. The individual will be responsible for training and coordinating the execution of screening projects with his/her team of 2 research associates, and he/she will be working with cross-functional teams and external partners. The individual will require creativity and flexibility to develop and build durable automated processes to scale up complex biological systems and work with our Informatics and Computational Biology teams to help implement processes.

　　Key Responsibilities:

　　As the Manger of Screening and Sample Management, you will be responsible for:

　　Experienced team lead to apply high throughput technologies to identify, characterize and select CRISPR/CAS9 and Cas12a therapeutic RNP and LNP candidates.

　　Work collaboratively across several therapeutic projects to develop and run cell assay models.

　　Cell models include human and mouse cell lines, primary human T-cells, hematopoietic and other cell types.

　　Managing the generation, QC, LIMS tracking and distribution of research grade editing reagents for internal projects and external partnerships.

　　Requirements

　　Required Qualifications:

　　The ideal candidate will:

　　Apply process-based approach to standardize assays for high-throughput applications.

　　Utilize liquid handling robotics and assay plate handling platforms to scale processes with automation and enable accessibility across the organization.

　　Have extensive knowledge of automated LNP formulations, QC and screening.

　　Utilize various endpoint readouts including NGS, FACS, RT-qPCR and other protein and pathway-based detection platforms.

　　Have a strong intellectual presence within projects, defining key project needs and timelines, analyzing and managing large screening data sets and presenting results and recommendations.

　　Experience managing direct reports.

　　Preferred Qualifications:

　　Additionally, candidates with the following attributes are preferred:

　　BS/MS with 10+ years of related experience, with minimum 5 years industry experience.

　　Track record of successful high throughput screening using standard liquid handling automation.

　　Minimum 2 years managerial experience.

　　Evidence of scientific achievement and acumen based on education, publications, public presentations and previous experience.

　　Ability to lead and collaborate across an organization.

　　Strong written and verbal communication skills.

　　Benefits

　　Benefits Summary:

　　Editas provides a comprehensive array of benefits to all employees, including a Blue Cross Blue Shield PPO Medical Plan, a company-funded Health Savings Account, Dental and Vision Insurance, Life and Disability Insurance, Dependent Care Account, Tuition Reimbursement, 401(k) plan with company match, Employee Stock Purchase Plan, Employee Assistance Plan, Wellness Programs, and a flexible Paid Time Off policy.

　　If you are a results-focused and collaborative professional with a passion for advancing transformative therapies, we invite you to apply. Join us at the forefront of genetic innovation and be a key contributor to Editas Medicine's mission of redefining healthcare through cutting-edge genetic technologies.

　　Fostering Belonging. Fueling Innovation. Transforming Lives.