Associate Technical Specialist/Associate Scientist Tuberculosis

　　Req ID #: 221179

　　Location:

　　Beerse, BE, 2340

　　For 75 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe. Whether your background is in life sciences, finance, IT, sales or another area, your skills will play an important role in the work we perform. In return, we’ll help you build a career that you can feel passionate about.

　　Job Summary

　　We are seeking a highly motivated Associate Technical Specialist/Associate Scientist to join our insourced Discovery team located in Beerse. The Associate Technical Specialist will mainly develop, conduct, and manage various in vitro M. tuberculosis microbiology and biochemical assays to assess compound efficacy, for our client. The successful candidate will also assist to conduct profiling assays, help with in vivo endpoints and will use a variety of technologies (bacterial CRIPRi libraries, bacterial extracellular flux analysis, etc.). All this is done in a team-oriented, result driven, international research environment that provides an excellent career opportunity for an enthusiastic and motivated technician.

　　Job Responsibilities

　　• Develop, optimize, validate and perform in vitro M. tuberculosis molecular, biochemical and mutant generation assays.

　　• Perform in vitro M. tuberculosis kill kinetic assays under different in vitro growth conditions.

　　• Maintenance of bacterial and compound stocks.

　　• Perform data analysis and establish an understanding of the relevance of the data being generated on the project.

　　• Present own work confidently, internally, with clear rationale and produce slides on own work and contribute the publication of scientific papers when requested.

　　• Write up lab book to department and patent-acceptable standard.

　　• Use appropriate scientific literature to plan assays.

　　• Trouble solving during assay development and assay execution.

　　• Be aware of the relevant scientific literature and contemporary laboratory practices.

　　• Work closely with the client team and ensure high quality support for projects.

　　Job Qualifications

　　Skills and experience required

　　• Bachelor or Master of Science in a relevant discipline

　　• Up to 3 years of working experience in a relevant environment.

　　• Hands-on experience with bacterial or viral pathogens.

　　• Experience working in a Biosafety Level 3 laboratory is a plus.

　　• Experience with in vivo animal work is a plus.

　　• Experience in a Pharma environment.

　　• Lab experience in different bacterial culturing techniques, assay development and/or compound profiling.

　　• Proficient in prokaryotic molecular biology techniques (DNA/RNA isolation, RT-PCR, DNA, etc.).

　　• Excellent communication skills in English.

　　• Excellent time management skills, able to prioritise tasks as needed and work closely with management to ensure high quality support for our client.

　　• Proficient in use of standard Microsoft Office Suite (Word, Excel, PowerPoint, Teams, OneNote, SharePoint). Experience in data analysis programs such as GraphPad is a plus.

　　What We Offer You

　　• A very comprehensive benefits package from day one.

　　• Global opportunities and strong career progression.

　　• The chance to work on several varied projects and liaise globally and nationally with other business areas.

　　• To be able to make a difference to health and wellbeing of people.

　　• To continue your own career growth.

　　• Well-being support and initiatives.

　　About Discovery

　　Discovery from Charles River is industry-proven in the successful development of novel therapies, with over 320 patents and 74 preclinical drug candidates delivered to our sponsors in the past 17 years. Backed by more than 650 scientists, our comprehensive, integrated portfolio employs the latest technology and platforms to provide chemistry, biology, and pharmacology services that support clients from the earliest stages of hit identification all the way through to IND. Our client-focused, collaborative approach creates true partnerships that anticipate challenges, overcome obstacles, and move us forward together on the journey of getting new drugs to market.

　　About Charles River

　　Charles River is an early-stage contract research organization (CRO). We have built upon our foundation of laboratory animal medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice (GLP) and non-GLP, to support clients from target identification through preclinical development. Charles River also provides a suite of products and services to support our clients’ clinical laboratory testing needs and manufacturing activities. Utilizing this broad portfolio of products and services enables our clients to create a more flexible drug development model, which reduces their costs, enhances their productivity and effectiveness to increase speed to market.

　　With over 20,000 employees within 110 facilities in over 20 countries around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our client’s unique challenges. Our client base includes global pharmaceutical companies, biotechnology companies, government agencies and hospitals and academic institutions around the world.

　　At Charles River, we are passionate about our role in improving the quality of people’s lives. Our mission, our excellent science and our strong sense of purpose guide us in all that we do, and we approach each day with the knowledge that our work helps to improve the health and well-being of many across the globe. We have proudly supported the development of 86% of the drugs approved by the FDA in 2021.

　　Equal Employment Opportunity

　　Charles River Laboratories is an Equal Opportunity Employer - all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, or national origin, veteran or disability status.

　　If you are interested in applying to Charles River Laboratories and need special assistance or an accommodation due to a disability to complete any forms or to otherwise participate in the resume submission process, please contact a member of our Human Resources team by sending an e-mail message to [email protected] . This contact is for accommodation requests for individuals with disabilities only and cannot be used to inquire about the status of applications.

　　For more information, please visit www.criver.com.