The Position

　　As an Associate Director for preclinical PK/PD Modelling and Simulation - Cardiometabolic, you will be an integral part of our multidisciplinary teams and drive our ‘learn-and-confirm’ mentality. You will improve your leadership skills and expand your own skillset by guiding PK/PD modelling scientists and project team representatives for all drug metabolism and pharmacokinetic disciplines or by directly guiding Project Teams within Discovery Research.

　　The mission of our Global Research Department ‘Drug Discovery Sciences’ is to find state-of-the-art NCE drug candidates. Our ambition is to strongly contribute to breakthrough therapeutic concepts, to provide excellence in drug screening, profiling, and optimization and, finally, to ensure seamless transition of drug candidates to Development. Apply now and join our Modelling & Simulation Team at the company’s largest Research & Development site.

　　This position is part time eligible with 70%.

　　Tasks & responsibilities

　　In your new role as an Associate Director in Preclinical PK/PD Modelling and Simulation, you will coordinate our preclinical NCE modelling and simulation resources in the field of cardiometabolic diseases, e.g., MASH and Obesity.

　　In addition, you will guide, shape, and implement PK/PD modelling strategies and overarching translational approaches for cardiometabolic indications, and contribute to the definition of modelling-related goals for Discovery Research.

　　By providing expertise and guidance with regards to pharmacokinetics and pharmacodynamics, you will ensure the timely delivery of state-of-the-art modelling and simulation deliverables throughout drug discovery as well as high-quality prediction of the human efficacious dose.

　　You will represent and coordinate Research DMPK disciplines in international Research Project Teams including the establishment and maintenance of external collaborations and the support of licensing activities.

　　Moreover, you will guide and support the development of three to five (junior and senior) research scientists.

　　Requirements

　　PhD with several years of experience in a field related to preclinical PK/PD modelling, pharmacometrics, applied mathematics, systems biology, bioinformatics or similar, or alternatively Master’s degree with extensive expertise, preferably in the pharmaceutical sector

　　Proven skills in PK, PK/PD, PBPK, and / or longitudinal disease modelling.

　　Proficiency in (statistical) programming languages and pharmacometric tools like R, MATLAB, Phoenix WinNonLin, NONMEM

　　In-depth understanding of PK/PD modelling and simulation, as well as pharmacology and DMPK-related topics. Experience in preclinical drug discovery and in cardiometabolic indications is beneficial

　　Successful track record of managing and developing direct reports is beneficial.

　　Enthusiastic personality, with a willingness to grow and succeed both individually and together with the team

　　Excellent communication skills in English with the ability to motivate a team

　　Ready to contact us?

　　Please contact our HR Direct Team, Tel: +49 (0) 6132 77-3330.

　　Recruitment process:

　　Step 1: Online application - application deadline is February 12th, 2024

　　Step 2: Virtual meeting in the period from beginning till mid of February

　　Step 3: On-site interviews in the period from beginning till mid of March

　　Discover our Biberach site: xplorebiberach.com

　　All qualified applicants will receive consideration for employment without regard to a person’s actual or perceived race, including natural hairstyles, hair texture and protective hairstyles; color; creed; religion; national origin; age; ancestry; citizenship status, marital status; gender, gender identity or expression; sexual orientation, mental, physical or intellectual disability, veteran status; pregnancy, childbirth or related medical condition; genetic information (including the refusal to submit to genetic testing) or any other class or characteristic protected by applicable law.