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Senior Director, Zavegepant and Migraine Life Cycle
Senior Director, Zavegepant and Migraine Life Cycle-January 2024
Collegeville
Jan 11, 2026
ABOUT PFIZER
Pfizer is a pharmaceuticals and biotechnology company.
10,000+ employees
Biotechnology, Manufacturing
VIEW COMPANY PROFILE >>
About Senior Director, Zavegepant and Migraine Life Cycle

  ROLE SUMMARY

  Currently there are more than 1 billion people who suffer from migraines worldwide, making this one of the largest population health challenges of our times.Zavegepant is the first and only calcitonin gene related peptide (CGRP) receptor antagonist nasal spray for the acute treatment of migraine in adults. Zavegepant has been approved in the US in March 2023 under the brand name ZAVZPRET and will be commercialized across IDM, Emerging Markets and China after regulatory submissions and approvals.

  NURTEC ODT /VYDURA (Rimegepant) is the first and only oral CGRP receptor antagonist for the acute and preventive treatment of migraine and is approved in the U.S., Canada, Switzerland, EU, UK, and several emerging markets (including UAE, Kuwait, Mexico, Central America) with approvals pending across markets worldwide over the next few years. Rimegepant has the opportunity to change the paradigm in migraine treatment and potentially establish a new standard of care.

  The Sr. Director, Zavegepant Lead & Migraine Lifeicycle Lead is a critical role to ensure successful launches of Zavegepant and Rimegepant and for delivering global value within the portfolio.

  ROLE RESPONSIBILITIES

  Lead Global marketing strategies and cross-functional team to commercialize Zavegepant globally. Develop brand strategy, differentiation strategies vs. the competition

  Partner with R&D, GAV and CSI to design Zavegepant clinical program to ensure registration and optimal reimbursement in IDM, EM and China markets

  Refine Zavegepant forecasts, launch sequencing, operational launch timelines globally and regionally to maximize asset value

  Provide clear commercial perspective to enable strategic and resource decisions from PGS, and partner with PGS to address patient needs for Zavegepant multi-dose intranasal formulations while reducing COGS.

  Lead team driving commercial efforts and setting strategy for the migraine portfolio by developing Zavegapant/Rimegepant co-positioning strategy, forecasts, and strategic plans for potential future indications and product launches.

  Providing strategic direction for competitive planning to ensure the portfolio continues to grow (through both competitive intelligence and global commercial interventions) amongst a highly competitive market.

  Provide expertise and hands-on partnership to Global Marketing lead, Regional Presidents, Country Managers, IDM and EM Chief Commercial Officer as technical/functional expert and advisor to address local issues

  Partner with regions / countries on strategic scenario planning or deep dive analyses to identify key enablers/derailers and build plans and actions, including rallying internal or external support/functional expertise needed

  Lead Lifecycle planning, generation of new data and real world evidence in partnership with medical, regulatory, R&D, GAV colleague; assessing what data will be of greatest strategic value and appropriately prioritizing data needs across markets

  Continually assess competitive environment, new product launches and competitive clinical data to determine migraine portfolio competitive strategy & response

  BASIC QUALIFICATIONS

  BA or BS required; MBA preferred

  Minimum 15+ years commercial pharmaceutical industry experience in marketing, strategy, new product launch, business development in pharmaceutical, medical device or biotechnology companies

  Prior experience with US and/or global product launch and lifecycle management preferred

  Experience interfacing/collaborating with in-country marketing, medical affairs, regulatory, and PGS

  Strong strategic skills, ability to make trade off decisions, evaluate business opportunities, build and sell in business cases

  Ability to work independently across senior level stakeholders and demonstrate judgement of what needs to be escalated

  Excellent communication and presentation skills (oral and written)

  Strong project management skills with demonstrated ability to lead large and diverse cross-functional teams and country teams

  Excellent leadership skills and ability to lead diverse cross-functional teams

  Candidate demonstrates a breadth of diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact.

  PREFERRED QUALIFICATIONS

  Business/Commercial Development experience for lifecycle opportunities

  Migraine/CNS experience is highly preferred

  Last Day to Apply: February 6, 2024

  The annual base salary for this position ranges from $191,300.00 to $318,800.00. In addition, this position is eligible for participation in Pfizer's Global Performance Plan with a bonus target of 22.5% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life's moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site - U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.

  Relocation assistance may be available based on business needs and/or eligibility.

  Sunshine Act

  Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

  EEO & Employment Eligibility

  Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

  Marketing and Market Research

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