HOW MIGHT YOU DEFY IMAGINATION?

　　You’ve worked hard to become the professional you are today and are now ready to take the next step in your career. How will you put your skills, experience and passion to work toward your goals? At Amgen, our shared mission—to serve patients—drives all that we do. It is key to our becoming one of the world’s leading biotechnology companies, reaching over 10 million patients worldwide. Come do your best work alongside other innovative, driven professionals in this meaningful role.

　　Senior Scientist

　　Live

　　What you will do

　　Let’s do this. Let’s change the world. The Department of Cardiometabolic Disorders at AMGEN Inc. is currently seeking a dedicated scientist to contribute to our research efforts in developing new treatments for cardiometabolic diseases. This role requires a commitment to developing a deep understanding of the pathogenic mechanisms that underlie obesity. In this vital role, you will be driving discovery efforts to identify how Amgen’s innovative biological modalities can improve the lives of patients who suffer from heart failure and related co-morbidities.

　　Key Responsibilities:

　　Identification of new therapeutic targets and preclinical validation. The candidate is expected to be continuously aware of scientific developments in cardiometabolic disease, with an emphasis on obesity.

　　Work collaboratively with a team of expert cardiometabolic scientists.

　　Present research discoveries to AMGEN colleagues and scientific meetings (oral or poster presentations and publish scientific papers in peer-reviewed journals).

　　Lead ethical, high-quality research experiments in accordance with regulatory agencies and compliance guidelines.

　　Design or assist in the development of medium to low-throughput assays used to support both small and large molecule drug development programs.

　　Design and implement in vitro, ex vivo. It is critical that the candidate is familiar with the pathophysiology of heart diseases and related co-morbidities.

　　Independently design, perform, and analyze laboratory experiments, including troubleshooting, optimization of assays, data collection, interpretation, biostatistical analysis, and presentation.

　　Participation in cross-functional drug development teams as a key intellectual and technical contributor.

　　Function optimally in a team-based or collaborative environment as part of a highly integrated team, possess excellent organizational, verbal, and written communication skills, and demonstrate the ability to produce reliable and reproducible results.

　　Win

　　What we expect of you

　　We are all different, yet we all use our outstanding contributions to serve patients. The senior scientist we seek is technically adept with these qualifications.

　　Basic Qualifications:

　　Doctorate degree PhD OR PharmD OR MD [and relevant post-doc where applicable]

　　Master’s degree and 3 years of relevant experience OR

　　Bachelor’s degree and 5 years of relevant experience

　　Preferred Qualifications:

　　PhD with a degree in biology or a related discipline.

　　5 or more years of experience in cardiometabolic research in industry or academic settings.

　　Willing to work in a team environment and possess good laboratory documentation skills.

　　Postdoctoral research experience.

　　Ability to perform in vitro assays to dissect the mechanism of action of therapeutic molecules in cardiac myocytes, fibroblasts, adipocytes, endothelial cells, and other relevant cardiac cell types.

　　In vitro experience with cultured cell lines, siRNA transfection techniques, western blotting, quantitative PCR techniques, RNA/DNA isolation, laboratory automation, high-content imaging technology, and fluorescence microscopy.

　　Thrive

　　What you can expect of us

　　As we work to develop treatments that take care of others, we also work to care for our teammates’ professional and personal growth and well-being.

　　Amgen offers a Total Rewards Plan comprising health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities including:

　　Comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts.

　　A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan

　　Stock-based long-term incentives

　　Award-winning time-off plans and bi-annual company-wide shutdowns

　　Flexible work models, including remote work arrangements, where possible

　　Apply now

　　for a career that defies imagination

　　Objects in your future are closer than they appear. Join us!

　　careers.amgen.com

　　Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

　　We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.