Job ID359232 LocationTwin Cities Job FamilyResearch-Researchers Full/Part TimeFull-Time Regular/TemporaryRegular Job Code8352R1 Employee ClassCivil Service About the Job The lab of is seeking a Researcher 1 to join our team. The Cvetanovic lab aims to understand how different brain cells and their interactions influence the onset and progression of neurodegenerative diseases. In particular we study the involvement of astrocytes and microglia in the pathogenesis of inherited neurodegenerative disease Spinocerebellar ataxia type 1(SCA1). SCA1 belongs to the family of polyglutamine diseases, that include Huntington's disease as it is caused by the expansion of CAG repeat (encoding for glutamine) in the coding region of Ataxin-1 gene. To do this we are using mouse genetics, cell and molecular biology techniques, mouse behavior, confocal microscopy and flow cytometry. The ultimate goal is to increase knowledge of the cellular and molecular pathways that underlie pathology of neurodegenerative disorders and open new avenues for therapeutic approaches. Another main focus of the lab is to train the next generations of scientists by creating the supportive environment that is conductive to learning, creating and testing new ideas. Job Duties: 70% Conduct research into the cellular and molecular mechanisms of the development and progression of neurodegenerative diseases using iPSCs. 20% Lab maintenance: including ordering supplies, compliance with university research standards, and maintenance of mouse colony. 10% Supervise undergraduate students Qualifications Required Qualifications (must be mentioned on application/resume): A Bachelor's degree with specialization in a biological science discipline, or an equivalent combination of education in the specific or related field of science and work experience totaling at least four years. Computer experience. Must be able to and comfortable with working with rodents. Preferred Qualifications: Hands-on experience with cell culture (sterile technique, cryopreservation), especially with iPSCs. Experience with immunocytochemistry, microscopy and imaging, molecular biology (PCR and qPCR, RNA purification, plasmid preparation, preparation of competent bacteria, basic sub-cloning, and western blot analysis) and maintenance of the mouse colony is desirable. Knowledge of Microsoft Office Adobe Photoshop, GraphPadPrism and Matlab is a plus. About the Department Neuroscience is the scientific study of the nervous system. It is an interdisciplinary science that collaborates with other fields such as chemistry, computer science, engineering, linguistics, mathematics, medicine and allied disciplines, philosophy, physics, and psychology. is committed to providing excellence in research, education, and public service. The Department of Neuroscience is part of the University of Minnesota's . The Medical School and related healthcare professional schools are grouped under the . Benefits Working at the University At the University of Minnesota, you'll find a flexible work environment and supportive colleagues who are interested in lifelong learning. We prioritize work-life balance, allowing you to invest in the future of your career and in your life outside of work. The University also offers a comprehensive benefits package that includes: Competitive wages, paid holidays, and generous time off Continuous learning opportunities through professional training and degree-seeking programs supported by the Low-cost medical, dental, and pharmacy plans Healthcare and dependent care flexible spending accounts University HSA contributions Disability and employer-paid life insurance Employee wellbeing program Excellent retirement plans with employer contribution Public Service Loan Forgiveness (PSLF) Financial counseling services Employee Assistance Program with eight sessions of counseling at no cost with free or reduced rates in the Twin Cities metro area Please visit the for more information regarding benefits. How To Apply Applications must be submitted online. To be considered for this position, please click the Apply button and follow the instructions. You will be given the opportunity to complete an online application for the position and attach a cover letter and resume. Additional documents may be attached after application by accessing your "My Job Applications" page and uploading documents in the "My Cover Letters and Attachments" section. To request an accommodation during the application process, please e-mail [email protected] or call (612) 624-UOHR (8647). Diversity As members of the Department of Neuroscience at the University of Minnesota, we are committed to excellence and compassionate conduct in research, education, and service. We recognize that transformative progress in these domains requires equity of access and opportunity to safe workplaces for all people, regardless of culture, race, ethnicity, socio-economic status, age, sexual orientation, gender identity and expression, physical capabilities, religious expression, country of origin, or immigration status. You can read more about our commitments . The University recognizes and values the importance of diversity and inclusion in enriching the employment experience of its employees and in supporting the academic mission. The University is committed to attracting and retaining employees with varying identities and backgrounds. The University of Minnesota provides equal access to and opportunity in its programs, facilities, and employment without regard to race, color, creed, religion, national origin, gender, age, marital status, disability, public assistance status, veteran status, sexual orientation, gender identity, or gender expression. To learn more about diversity at the U: Employment Requirements Any offer of employment is contingent upon the successful completion of a background check. Our presumption is that prospective employees are eligible to work here. Criminal convictions do not automatically disqualify finalists from employment. About the U of M The University of Minnesota, Twin Cities (UMTC) The University of Minnesota, Twin Cities (UMTC), is among the largest public research universities in the country, offering undergraduate, graduate, and professional students a multitude of opportunities for study and research. Located at the heart of one of the nation's most vibrant, diverse metropolitan communities, students on the campuses in Minneapolis and St. Paul benefit from extensive partnerships with world-renowned health centers, international corporations, government agencies, and arts, nonprofit, and public service organizations. At the University of Minnesota, we are proud to be recognized by the Star Tribune as a Top Workplace for 2021, as well as by Forbes as Best Employers for Women and one of America's Best Employers (2015, 2018, 2019, 2023), Best Employer for Diversity (2019, 2020), Best Employer for New Grads (2018, 2019), and Best Employer by State (2019, 2022). The University recognizes and values the importance of diversity and inclusion in enriching the employment experience of its employees and in supporting the academic mission. The University is committed to attracting and retaining employees with varying identities and backgrounds. The University of Minnesota provides equal access to and opportunity in its programs, facilities, and employment without regard to race, color, creed, religion, national origin, gender, age, marital status, disability, public assistance status, veteran status, sexual orientation, gender identity, or gender expression. To learn more about diversity at the U: http://diversity.umn.edu.