This job was posted by https://illinoisjoblink.illinois.gov : For moreinformation, please see:https://illinoisjoblink.illinois.gov/jobs/11611394 Department

　　BSD MED - Hematology and Oncology - Sweis Research Staff

　　About the Department

　　The University of Chicago is internationally renowned as a leader inCancer Immunology and Developmental Therapeutics, with research programsranging from basic scientific investigation to Phase I, II, and IIIclinical trials. The Section of Hematology/Oncology in the Department ofMedicine has a proud and long history of excellence in advancing cancercare through basic and translational discovery.

　　Job Summary

　　The Research Professional will lead cancer immunology projects in theSweis laboratory (sweislab.org). The laboratory is investigatingmechanisms of cancer immunotherapy resistance, through the use ofcutting-edge bladder cancer and skin cancer model systems. The positionrequires the ability to perform tasks independently and lead smallgroups within the lab on projects. Collaborations with otherlaboratories and investigators within the Section and Department areroutine.

　　With respect to laboratory technical skills, the individual must beproficient in cell/tissue culture, flow cytometry/sorting (FACS),protein isolation and analysis (western blot, ELISA, andimmunohistochemistry), RNA isolation and analysis by qRT-PCR, molecularbiology (PCR, genotyping, cloning plasmid constructs, DNA isolation andsequencing analysis, CRISPR). Knowledge of cancer immunology andadvanced experimental techniques such as single cell RNAseq or specialtranscriptomics is preferred. The individual must be comfortable withmouse modeling (husbandry/breeding, genotyping, surgical procedures,drug administration by oral gavage, intraperitoneal and tail veininjection harvest, protein, RNA and immunohistochemical analysis).

　　The professional will also be expected to train new members of thelaboratory. Finally, the candidate will be expected to generatemanuscripts, formulate grant proposals, and present research at majorconferences.

　　Responsibilities

　　Molecular biology - PCR, genotyping, cloning plasmid constructs, DNAisolation and sequencing analysis.Cell culture - in vitro experiments, retroviral transductions,CRISPR.Mouse work - maintenance of colonies, running experiments in mice.Immunoassays: Flow cytometry (FACS), ELISPOT, ELISA.Advanced experimental techniques (single cell sequencing, spatialtranscriptomics).Collate and analyze data.Maintain accurate, up-to-date and well-documented records ofprocedures performed and data generated.Summarize results, assist in interpreting findings, and generatemanuscripts and grants.Instruct new personnel including technologists, residents, medicalstudents, or fellows.Collaborates on development of new research projects with academicand community-based organizations.May present work at scientific meetings.Performs other related work as needed.Minimum Qualifications

　　Education:

　　Minimum requirements include a PhD in related field.

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　　Work Experience:

　　Minimum requirements include knowledge and skills developed through---

　　Certifications:

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　　Preferred Qualifications

　　Education:

　　Doctoral degree in Cancer Biology or Cancer Immunology or relateddiscipline.Experience:

　　Prior biology/immunology laboratory experience.Preferred Competencies

　　The ability to work as part of a team and to be open minded andcooperative.The ability to apply new concepts and have a creative approach toproblem solving.Excellent verbal and written communication skills.The ability to organize your own work with minimal supervision andprioritize in response to deadlines.Application ocuments

　　Resume/CV (required)Cover Letter (preferred)When applying, the document(s) MUSTbe uploaded via the MyExperience page, in the section titled Application Documents ofthe application.

　　Job Family

　　Research

　　Role Impact

　　Individual Contributor

　　FLSA Status

　　Exempt

　　Pay Frequency

　　Monthly

　　Scheduled

　　Weekly Hours

　　40

　　Benefits Eligible

　　Yes

　　Drug Test Required

　　No

　　Health Screen Required

　　No

　　Motor Vehicle Record Inquiry Required

　　No

　　Posting Statement

　　The University of Chicago is an Affirmative Action/EqualOpportunity/Disabled/Veterans and does not discriminate on the basis ofrace, color, religion, sex, sexual or