Job Description

　　Be a part of the legacy: Postdoctoral Research Fellow Program

　　Our Research Laboratories’ Postdoctoral Research Fellow Program aims to be a best-in-industry program for industrial postdoctoral researchers, designed to provide you with an academic focus in a commercial environment. With the resources, reach, and expertise of a large pharmaceutical company, postdoctoral researchers will be positioned to excel in an institution committed to breakthrough innovation in research and discovery.

　　The Neuroscience Discovery department within our company's Research Labs (West Point, PA) is seeking a motivated Postdoctoral Fellow with expertise in cellular and molecular biology, protein biochemistry, lysosome biology and a strong interest in Neuroscience drug discovery. The successful candidate will use a combination of molecular and cell biological techniques to study the molecular mechanisms of lysosomal function under physiological and pathophysiological conditions of neurodegeneration, to increase understanding of the disease processes for Alzheimer’s disease, Parkinson’s disease and ALS.

　　The postdoctoral fellow will work in close collaboration with cell biologists, neuroscientists, geneticists, electrophysiologists, and chemists, across our company's network to execute a research project with the goal of publishing the results in peer-reviewed journals.

　　Position Qualifications :

　　Education Minimum Requirement:

　　Candidates must currently hold a PhD or will you have completed your PhD within the next year in Neuroscience, molecular biology, cell biology, biochemistry, or genetics.Required Experience and Skills:

　　Minimum of 3 -year cell culture experience with immortalized mammalian, primary, or iPSC-derived cells

　　Manipulation of gene-expression via siRNA and viral mediated transduction

　　In-depth skills to run biochemical and molecular assays (Western blotting, qPCR, ELISA, Immunoprecipitation, and qPCR)

　　Experience in imaging (immunocytochemistry, confocal imaging, or high content imaging)

　　Expertise in and knowledge of neurobiology in the context of neurodegeneration

　　Excellent communication skills (written, presentation, and oral)

　　Ability to work in team settings in a highly collaborative environment.

　　Ability to work effectively and flexibly within timelines on multifaceted projects.

　　Demonstrated ability to prepare peer-reviewed publications.

　　No more than 1 year of post-doctoral experience

　　Preferred Experience and Skills:

　　Demonstrated skill sets and experience in for studying lysosome or mitochondrial biology in the context of neurodegeneration.

　　Co-culture of neuron and glia

　　Responsibilities include:

　　Generation and culture of immortalized, primary, and iPSC-derived cell lines

　　Develop and validate imaging and biochemical assays in multi-well format.

　　Design, conduct, and analyze transcriptomics, proteomics, lipodomics experiments.

　　Sharing scientific progress in regular internal team meetings and external scientific conferences

　　Write and submit publications to peer-reviewed journals.

　　MRLpostdoc

　　NOTICE FOR INTERNAL APPLICANTS

　　In accordance with Managers' Policy - Job Posting and Employee Placement, all employees subject to this policy are required to have a minimum of twelve (12) months of service in current position prior to applying for open positions.

　　If you have been offered a separation benefits package, but have not yet reached your separation date and are offered a position within the salary and geographical parameters as set forth in the Summary Plan Description (SPD) of your separation package, then you are no longer eligible for your separation benefits package. To discuss in more detail, please contact your HRBP or Talent Acquisition Advisor.

　　Employees working in roles that the Company determines require routine collaboration with external stakeholders, such as customer-facing commercial, or research-based roles, will be expected to comply not only with Company policy but also with policies established by such external stakeholders (for example, a requirement to be vaccinated against COVID-19 in order to access a facility or meet with stakeholders). Please understand that, as permitted by applicable law, if you have not been vaccinated against COVID-19 and an essential function of your job is to call on external stakeholders who require vaccination to enter their premises or engage in face-to-face meetings, then your employment may pose an undue burden to business operations, in which case you may not be offered employment, or your employment could be terminated. Please also note that, where permitted by applicable law, the Company reserves the right to require COVID-19 vaccinations for positions, such as in Global Employee Health, where the Company determines in its discretion that the nature of the role presents an increased risk of disease transmission.

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　　We are an Equal Opportunity Employer, committed to fostering an inclusive and diverse workplace. All qualified applicants will receive consideration for employment without regard to race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status, or other applicable legally protected characteristics. For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit:

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　　U.S. Hybrid Work Model

　　Effective September 5, 2023, employees in office-based positions in the U.S. will be working a Hybrid work consisting of three total days on-site per week, generally Tuesday, Wednesday and either Monday or Thursday, although the specific days may vary by site or organization, with Friday designated as a remote-working day, unless business critical tasks require an on-site presence. This Hybrid work model does not apply to, and daily in-person attendance is required for, field-based positions; facility-based, manufacturing-based, or research-based positions where the work to be performed is located at a Company site; positions covered by a collective-bargaining agreement (unless the agreement provides for hybrid work); or any other position for which the Company has determined the job requirements cannot be reasonably met working remotely. Please note, this Hybrid work model guidance also does not apply to roles that have been designated as “remote”.

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　　Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.

　　Employee Status:

　　Regular

　　Relocation:

　　Domestic

　　VISA Sponsorship:

　　Yes

　　Travel Requirements:

　　10%

　　Flexible Work Arrangements:

　　On-Site

　　Shift:

　　Not Indicated

　　Valid Driving License:

　　No

　　Hazardous Material(s):

　　NA

　　Requisition ID: R275689