About the Role

　　Location: Basel, Switzerland

　　Role Purpose:

　　Join us in a ground breaking role as a formulation Project Leader (FPL) for Oligonucleotides, where you will have the opportunity to work on innovative parenteral formulations and contribute to the development of patient-centric drugs. This role is perfect for someone who is passionate about bringing transformational medicines to the market and working on exciting novel pharmaceutical products.

　　Key Responsibilities

　　• Responsible for the design, execution and delivery of formulation and process development studies for liquid and lyophilized parenteral drug products of biologics (e.g. oligonucleotides), small molecules and long acting injectable

　　• Develop and implement formulation, primary packaging (container closure system), and dosage form configuration to ensure stability, manufacturability, reliability and customer satisfaction.

　　• Critically review and interpret raw data and information. Interprets results and proposes next steps

　　• Ensure documentation of work (e.g. development reports, support for preparation of regulatory documents)

　　• Regularly contribute to improvements, explore new technologies and lead integration of activities across scientific areas

　　• Enable innovation, support technical strategy projects, generate intellectual property and evaluate and implement new methods and technologies

　　Diversity & Inclusion / EEO

　　We are committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve.

　　Role Requirements

　　Qualifications

　　• Ph.D. in Chemistry or related fields with 2+ years of biopharmaceutical experience in Oligonucleotide (mRNA, siRNA, ASO) or Biologic field (ADC, proteins) OR Master degree with 5+ years pharmaceutical experience OR Bachelor degree with 8+ years biopharmaceutical experience respectively, with proven formulation development (parenteral, aseptic, solution and/or suspension) and manufacturing process or related expertise.

　　• Expertise and knowledge in oligonucleotide delivery preferable.

　　• Experience with aseptic Drug Product manufacturing of oligonucleotides including process transfer and QbD design.

　　• Experience with devices (pre-filling syringes, vial, combination product)

　　• Experience with in-use compatibility study and Instruction for use preparation.

　　• Experience with process development and regulatory issues parenteral Drug Product clinical-grade manufacturing a plus.

　　Why Novartis? Our purpose is to reimagine medicine to improve and extend people's lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture

　　You'll receive: You can find everything you need to know about our benefits and rewards in the Novartis Life Handbook. https://www.novartis.com/careers/benefits-rewards

　　Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

　　Accessibility and accommodation

　　Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to [email protected] and let us know the nature of your request and your contact information. Please include the job requisition number in your message.

　　Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network

　　Division

　　Development

　　Business Unit

　　TECHNICAL R & D GDD

　　Location

　　Switzerland

　　Site

　　Basel

　　Company / Legal Entity

　　Novartis Pharma AG

　　Functional Area

　　Research & Development

　　Job Type

　　Full Time

　　Employment Type

　　Regular

　　Shift Work

　　No