Job Family :

Biologist (Digital)

Travel Required :

None

Clearance Required :

Ability to Obtain Public Trust

What You Will Do :

We are currently searching for a Chemist to independently provide support services to satisfy the overall operational objectives of the National Center for Advancing Translational Sciences (NCATS), Therapeutics Development Branch (TDB). The target candidate needs experience related to chemical process development and scale-up synthesis activities and an understanding of Good Manufacturing Practices (GMP) concepts. This is a full-time, on-site opportunity in Rockville, MD.

Perform synthetic route scouting.

Perform process development of scale-up synthesis activities.

Formulate chemistry plans for the development of soluble, potent, selective small molecule probes of biological function.

Perform bulk-synthesis, purification, and formulation efforts for advanced testing in animal models.

Maintain up-to-date electronic laboratory notebook detailing all experiments and associated online databases.

Gather, analyze and interpret data; prepare summaries and reports.

Search chemical databases for journal articles, patents and related technologies.

Troubleshoot issues, maintain, and train users on scientific instrumentation and equipment.

Prepare reagents and maintain an active inventory of all chemicals kept in the laboratory.

Purify compounds by preparative chromatography from chemists.

Perform chemical and biochemical reactions and appropriate analytical analyses, including chemical synthesis and optimization of small molecules probes and organic synthesis of key materials such as reference compounds).

Analyze samples using validated analytical methods for ongoing studies.

Develop and make recommendations on experimental procedures and research protocols including novel chemistry methodologies and technologies that advance the field and develop plans for novel syntheses and approaches to new compounds.

Collaborate with staff to evaluate and/or develop new techniques.

What You Will Need :

Master’s degree in chemistry

At least ONE (1) year of experience in a chemistry laboratory environment.

Must have experience with either process development or scale-up synthesis activities

Must be familiar with common techniques such as Microscopy, Mass Spectrometry, Spectrophotometry, Chromatography technologies, X-Ray crystallography, or Thermal analytical technologies.

MS Office suite

What Would Be Nice To Have :

Experience with Kilo Lab or pilot plant desired

Beneficial to be familiar with common microscopy techniques such as Confocal, Electron, Multi Photon, Fluorescence, or Super Resolution Nuclear Magnetic Resonance Microscopy

Beneficial to be familiar with common chromatography techniques such as HPLC, UPLC, GC, IC, or thin layer.

Manuscript writing preferred

The annual salary range for this position is $57,300.00-$85,900.00. Compensation decisions depend on a wide range of factors, including but not limited to skill sets, experience and training, security clearances, licensure and certifications, and other business and organizational needs.

What We Offer:

Guidehouse offers a comprehensive, total rewards package that includes competitive compensation and a flexible benefits package that reflects our commitment to creating a diverse and supportive workplace.

Benefits include:

Medical, Rx, Dental Vision Insurance

Personal and Family Sick Time Company Paid Holidays

Parental Leave

401(k) Retirement Plan

Group Term Life and Travel Assistance

Voluntary Life and ADD Insurance

Health Savings Account, Health Care Dependent Care Flexible Spending Accounts

Transit and Parking Commuter Benefits

Short-Term Long-Term Disability

Tuition Reimbursement, Personal Development, Certifications Learning Opportunities

Employee Referral Program

Corporate Sponsored Events Community Outreach

Care.com annual membership

Employee Assistance Program

Supplemental Benefits via Corestream (Critical Care, Hospital Indemnity, Accident Insurance, Legal Assistance and ID theft protection, etc.)

Position may be eligible for a discretionary variable incentive bonus

About Guidehouse

Guidehouse is an Equal Employment Opportunity / Affirmative Action employer. All qualified applicants will receive consideration for employment without regard to race, color, national origin, ancestry, citizenship status, military status, protected veteran status, religion, creed, physical or mental disability, medical condition, marital status, sex, sexual orientation, gender, gender identity or expression, age, genetic information, or any other basis protected by law, ordinance, or regulation.

Guidehouse will consider for employment qualified applicants with criminal histories in a manner consistent with the requirements of applicable law or ordinance including the Fair Chance Ordinance of Los Angeles and San Francisco.

If you have visited our website for information about employment opportunities, or to apply for a position, and you require an accommodation, please contact Guidehouse Recruiting at 1-571-633-1711 or via email at [email protected] . All information you provide will be kept confidential and will be used only to the extent required to provide needed reasonable accommodation.

Guidehouse does not accept unsolicited resumes through or from search firms or staffing agencies. All unsolicited resumes will be considered the property of Guidehouse and Guidehouse will not be obligated to pay a placement fee.