Description:
We are looking for an experienced Research Associate/ Senior Research Associate to help the Discovery Sciences team accelerate our search for new oncology therapeutics. The successful candidate will join a high-performing team of experts in the use of biochemical and biophysical screening techniques to drive the efficient identification and rapid development of clinically impactful drugs against frontier targets in oncology. Working from the bench, they will apply their biochemical and biophysical expertise. The candidate will support Discovery Science efforts to enhance how we discover inhibitors of established and new drug target proteins, as well as contribute to our mission of providing high-quality experimental data for existing programs.
Skills:
biochemisty, biochemical assays, method development, isothermal caliometry, ITC, data processing, genedata
Additional Skills & Qualifications:
Required Experience, Skills, and Education:
• Bachelor’s degree with 2-5 years of experience or Master’s degree with 0-3 years of experience in biochemistry, biophysics, biotechnology, or related field.
• Experience with biochemical/biophysical assay development, validation, and troubleshooting
• Proficiency in execution of in vitro biochemical and biophysical assays suitable for the discovery, validation, or mechanistic characterization of target molecules (ITC, SPR/BLI, TR-FRET, fluorescence polarization, etc.).
• Familiarity with data processing and visualization tools for data analysis and figure generation (e.g., GraphPad Prism, R, Genedata Screener, Vortex, etc).
• Attention to detail with excellent organizational, experimental data recording, and time management skills
• Excellent written and verbal communication skills.
• Innovative, team-player and a demonstrated willingness to learn in a fast-paced environment.
Additional Desired Skills:
• Isothermal titration calorimetry (ITC) experiment execution and data analysis experience
• Familiarity with automated liquid handling (SPT Dragonfly and/or Mosquito, Agilent Bravo, Tecan)
• Experience with high throughput screening
• Facile with instrumentation, able to trouble shoot problems and work with engineers to generate successful solutions to technical limitations.
• Rigorous, quantitative, detail-oriented experimentalist with an understanding of statistics.
Diversity, Equity & Inclusion
At Actalent, diversity and inclusion are a bridge towards the equity and success of our people. DE&I are embedded into our culture through:
Hiring diverse talent
Maintaining an inclusive environment through persistent self-reflection
Building a culture of care, engagement, and recognition with clear outcomes
Ensuring growth opportunities for our people
Actalent is an equal opportunity employer.
About Actalent
Actalent connects passion with purpose. We help visionary companies advance their engineering and science initiatives through access to specialized experts that drive scale, innovation, and speed to market. With a network of almost 30,000 engineering and sciences consultants and more than 4,500 clients across the U.S., Canada, Asia, and Europe, Actalent serves many of the Fortune 500. An operating company of Allegis Group, the global leader in talent solutions, Actalent launched as a new specialized engineering and sciences services and workforce solutions brand in 2021.