The AbbVie Ophthalmology Discovery Research group located in Irvine, CA is seeking a highly-motivated and experienced scientist to contribute to our research and discovery efforts to develop therapies for sight-threatening disease. S/he/they will be responsible for differentiating, characterizing, maintaining, and performing experiments with various cell culture model systems, including immortalized cell lines, primary cells, induced pluripotent stem cell (IPSC)-derived differentiated cells, and organoids. S/he/they will also follow-through on cell culture-based assays to investigate discovery of novel therapeutics. This position exists within a highly-collaborative environment, supporting multiple projects. The successful candidate will apply their passion, attention to detail, prior hands-on experience, and teamwork skills to support the Ophthalmology pipeline.

　　Responsibilities

　　• Independently perform routine and complex cell culture techniques

　　• Independently perform cell-based assays and experiments with a wide range of endpoints

　　• Generate and document high-quality experimental data to identify and confirm the mechanism of action of lead compounds, antibodies, and gene therapies

　　• Present data and findings to a variety of audiences, including project teams and extended research and discovery organization meetings

　　• Maintain an up-to-date understanding of new technologies and relevant scientific advances in support of our research goals

　　• Effectively collaborate with peers and teams

　　• On-site position with flexible schedule with rotating weekend and holiday work

　　• Scientist I - Bachelors or Masters in molecule biology, cell biology, immunology, neurobiology, or other biological science with 5+(BS) or 2+(MS) years of hands-on experience or Scientist II - Bachelors + 7 years of experience or Masters + 5 years of experience

　　• Demonstrated hands-on experience in cell culture, as well as cell and molecular biology techniques, including viability assays, transfection, PCR, and gel electrophoresis

　　• Previous hands-on experience with iPSC culture and differentiation towards ocular cells preferred

　　• Previous experience in designing and performing cell sorting (FACS and/or MACS) assays preferred

　　• Previous experience in high content screening preferred

　　• Must have strong written and verbal communication skills and the ability to effectively communicate with audiences of diverse backgrounds

　　• Highly motivated, self-driven, and results-oriented person, comfortable working independently in a fast-paced environment

　　• Demonstrate high degree of flexibility in adapting to different projects and personalities as well as excellent networking and relationship-building skills

　　Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:

　　· The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future.

　　· We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.

　　· This job is eligible to participate in our short-term incentive programs.

　　Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law.

　　AbbVie is committed to operating with integrity, driving innovation, transforming lives, serving our community, and embracing diversity and inclusion. It is AbbVie’s policy to employ qualified persons of the greatest ability without discrimination against any employee or applicant for employment because of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information, gender identity or expression, sexual orientation, marital status, status as a protected veteran, or any other legally protected group status.