About the Role

　　5600 scientists working on over 300 discovery programs in 8 disease areas focusing on 90 new molecular entities makes Novartis the premier place to develop your career as a pharmaceutical professional. If you are curious, scientifically minded, and want to positively impact society by speeding delivery of novel therapies to patients, then look no further, Novartis Biomedical Research is the place to be. As a Critical Reagent Manager in the Translational Medicine PK Sciences Bioanalytical group, you will have the opportunity to make a difference. If you have a collaborative nature, a commitment to teamwork across an organization and a relentless focus on improving patient care we want you to apply.

　　In this Critical Reagent Manager role, you will be part of the Critical Reagents group, coordinating the production and inventory management of biological reference standards and critical reagents used in internal and external bioanalytical laboratories. The position requires a strong scientific and laboratory background and project management skills with a focus on critical reagent production, handling, storage, management, and a customer service mindset. You will work with an elite team of scientists involved in the development and qualification of small and large molecule assays supporting pharmacokinetic, pharmacodynamic and immunogenicity studies across all phases of the drug discovery & development pipeline.

　　Your main responsibilities will include but are not limited to:

　　• Employ scientific expertise, strong organization and documentation skills to start, lead and coordinate the outsourced productions of customized critical reagents, by contributing to the production strategy, identifying and reviewing production protocols, requesting quotes, interacting with vendors, requesting funds, collecting and providing updates to stakeholders on production timelines.

　　• Coordinate the design strategies and production platforms to meet the team needs for the outsourced production, characterization and requalification of critical reagents from both Novartis Biologics database and in-licensing programs.

　　• Identify protocols for cloning, expression, purification and requalification of in-house monoclonal antibodies, recombinant proteins, Stable Isotope Labelled (SIL) proteins in different hosts (Escherichia coli, yeast, insect, mammalian cell cultures and hybridoma cultures).

　　• Provide scientific expertise and utilize strong collaboration skills to work with colleagues from various departments, stakeholders and external service providers to optimize processes to meet the needs for outsourced production, characterization and requalification of critical reagents.

　　• Work with colleagues from various departments and external service providers to optimize processes and inventory management systems to keep control over shipping and allow timely forecast of reproduction, labelling, resupply, requalification.

　　• Oversee logistics and inventory database maintenance, to ensure that service is provided with the appropriate quality and timeline.

　　• Provide technical and process troubleshooting and find suitable resolutions.

　　• Maintain up-to-date documentation, including documentation storage and archiving. Prepare technical documentation as required.

　　• Provide instruction and technical training to other scientific staff, contributing to team growth.

　　Diversity & Inclusion / EEO

　　We are committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve.

　　Role Requirements

　　What you bring to the role:

　　• PhD / Pharm. D. Level scientist with experience in a relevant field required.

　　• 4+ years in the pharmaceutical industry.

　　• Experience in planning, launching, and tracking outsourced production of customized reagents.

　　• Experience in working with cross functional teams in a highly dynamic, matrixed, project-team environment.

　　• Strong project management, critical thinking, and problem-solving skills.

　　• Ability to work independently with minimal supervision on assigned tasks.

　　• Experience in production of monoclonal antibodies, recombinant proteins, Stable Isotope Labelled (SIL) proteins in different hosts (Escherichia coli, yeast, insect, and mammalian cell cultures or hybridoma cultures), including cloning, upstream and downstream processes in biopharmaceutical environment.

　　• Experience in bioanalytical assays.

　　• Knowledge and experience with GLP/GMP requirements and familiarity with health authority expectations for bioanalytical assays.

　　• Experience in leading a small team will be an added value.

　　Why consider Novartis?

　　750 million. That's how many lives our products touch. And while we're proud of that fact, in this world of digital and technological transformation, we must also ask ourselves this: how can we continue to improve and extend even more people's lives?

　　We believe the answers are found when curious, courageous and collaborative people like you are brought together in an inspiring environment. Where you're given opportunities to explore the power of digital and data. Where you're empowered to risk failure by taking smart risks, and where you're surrounded by people who share your determination to tackle the world's toughest medical challenges.

　　We are Novartis. Join us and help us reimagine medicine.

　　Division

　　Biomedical Research

　　Business Unit

　　Translational Medicine

　　Location

　　Switzerland

　　Site

　　Basel

　　Company / Legal Entity

　　Novartis Pharma AG

　　Functional Area

　　Research & Development

　　Job Type

　　Full Time

　　Employment Type

　　Regular

　　Shift Work

　　No